Description
Latin name
Flebodia 600
packaging 15 pcs
Pharmacological action of
The drug Phlebodia 600 has phlebotonizing effect (reduces venous extensibility, increases venous tone (dose-dependent effect), reduces venous congestion), improves lymphatic drainage (increases the tone and frequency of reduction of lymphatic capillaries, increases their functional density, reduces lymphatic pressure) , improves microcirculation (increases capillary resistance (dose-dependent effect), reduces their permeability), reduces the adhesion of leukocytes to the venous wall and their moment ation paravenoznye in tissue, improves oxygen diffusion and perfusion in the skin tissue, has anti-inflammatory effect. Enhances the vasoconstrictor effect of adrenaline, norepinephrine, blocks the production of free radicals, the synthesis of prostaglandins and thromboxane.
Pharmacokinetics
Quickly absorbed from the gastrointestinal tract, detected in plasma 2 hours after administration. The maximum plasma concentration is reached 5 hours after administration. Evenly distributed and accumulated in all layers of the walls of the vena cava and saphenous veins of the lower extremities, to a lesser extent – in the kidneys, liver and lungs and other tissues. The selective accumulation of diosmin and / or its metabolites in the venous vessels reaches a maximum by 9 hours after administration and persists for 96 hours. It is excreted by the kidneys 79%, intestines – 11%, with bile – 2.4%.
Indications
As a part of complex therapy: elimination of symptoms of lymphovenous insufficiency of the lower extremities: feeling of heaviness or fatigue in the legs, pain
additional treatment for violation of microcirculation
acute hemorrhoids (symptomatic therapy).
Contraindications
hypersensitivity to the components of the drug Phlebodia 600
breastfeeding period
pregnancy (I trimester – experience with use is limited)
childhood (under 18 years).
Use during pregnancy and lactation
Until now, in clinical practice there have been no reports of any side effects when using the drug in pregnant women. The use during pregnancy in the II and III
trimesters is possible only as directed by the doctor in those cases when the expected benefit to the mother outweighs the potential risk to the fetus.
In experimental studies, no teratogenic effects on the fetus were detected. During breastfeeding, it is not recommended to take the drug, because there is no data on the penetration of the drug into breast milk.
, is not recommended. Dosage and Administration
Before using the drug, consult your doctor.
The drug is intended for oral administration.
With varicose veins of the lower extremities and chronic lymphovenous insufficiency (edema, pain, cramps), I tablet is prescribed per day in the morning on an empty stomach. The duration of therapy is usually 2 months. With exacerbation of hemorrhoids, the drug is prescribed for 2-3 tablets per day with meals for 7 days. If one or more doses of the drug is missed, it is necessary to continue the use of the drug in the usual mode and in the usual dose.
Side effects
In rare cases, hypersensitivity to the components of the drug (requiring a break in treatment).
From the gastrointestinal tract: dyspeptic disorders (heartburn, nausea, abdominal pain).
From the side of the central nervous system: headache.
If any of the side effects listed in the description are exacerbated, or the patient has noticed any other side effects not listed in the description, you should inform your doctor.
Storage conditions
Do not store above 30 ° C.
Shelf life
3 years.
Prescription drugstore
No prescription
dosage form
tablets
Prescription
Prescription
Pregnant as prescribed by a doctor, Adults prescribed by a doctor
Laboratory Innoter, France
