Description
Latin name
CURANTYL
Release form
Coated tablets.
packaging 120 pcs
Indications
Treatment and prevention of cerebrovascular accidents according to the ischemic type
discirculatory encephalopathy
primary and secondary prevention of coronary heart disease, especially with intolerance to acetylsalicylic acid
prevention of arterial and venous thrombosis and treatment of their complications
prevention of thromboembolism after surgery for prosthetic heart valves
prevention of placental insufficiency in complicated pregnancy
microcirculatory disorders of any type (as part of complex therapy and OR as an inducer of interferon and an immunomodulator) – for taking the drug in a dose of 25 mg.
Contraindications
hypersensitivity to the drug
acute myocardial infarction
unstable angina
common constrictive coronary atherosclerosis
subaortic stenosis, aortic
heart failure decompensation
hypotension
collapse
severe hypertension
severe cardiac arrhythmia
chronic obstructive pulmonary disease pulmonary
chronic renal failure
liver failure l
hemorrhagic diathesis
disease with an increased risk of bleeding (including peptic ulcer and duodenal ulcer).
Use during pregnancy and lactation
Use of the drug during pregnancy is possible according to indications.
The use of the drug during lactation is possible only if the expected benefit of the treatment exceeds the possible risk.
Composition
1 tablet contains:
Active substances:
dipyridamole 25 mg.
Excipients:
corn starch – 67.75 mg,
lactose monohydrate – 28.5 mg,
gelatin – 2.5 mg,
sodium carboxymethyl starch (type A) – 3.75 mg,
silicon dioxide anhydrous – 1.25 mg,
magnesium stearate – 1.25 mg.
Composition of the film coat:
hypromellose – 0.9 mg,
talc – 0.4 mg,
macrogol 6000 – 1.2 mg,
titanium dioxide (E171) – 0.1 mg,
dye quinoline yellow (E104) – 0.008 mg,
simethicone emulsion – 0.002 mg.
Dosage and administration of
The dose of the drug is selected depending on the severity of the disease and the individual response of the patient.
For coronary heart disease, 75 mg 3 times / day is recommended. If necessary, the daily dose can be increased under the supervision of a physician.
75 mg 3-6 times / day are prescribed for the prevention and treatment of cerebrovascular disorders, as well as for prevention. The maximum daily dose is 450 mg.
To reduce platelet aggregation, Curantyl is prescribed in a dose of 75-225 mg / day in several doses. In severe cases, the dose can be increased to 600 mg / day.
For the prevention of influenza and SARS, especially during epidemics, Curantil N25 and Curantil 25 are prescribed 50 mg (2 tablets or 2 tablets) / day in 1 dose. The drug is taken 1 time per week for 4-5 weeks.
For the prevention of ARVI recurrence in patients often suffering from respiratory viral infections, Curantil N25 and Curantil 25 are prescribed 100 mg / day (2 tablets or dragees 2 times / day with an interval between doses of 2 hours). The drug is taken 1 time per week for 8-10 weeks.
Tablets should be taken on an empty stomach, without breaking or cracking, with a small amount of liquid. The duration of the course of treatment is determined by the doctor.
Side effects of
From the cardiovascular system: palpitations, tachycardia (especially with the use of other vasodilators at the same time), bradycardia, flushing of the face, flushing of the face, coronary stealing syndrome (when using the drug at a dose of more than 225 mg / day) decreased blood pressure.
From the digestive system: nausea, vomiting, diarrhea, pain in the epigastric region. Usually, these side effects disappear with a longer use of the drug.
From the blood coagulation system: thrombocytopenia, changes in the functional properties of platelets, bleeding in isolated cases – increased bleeding during or after surgery.
From the side of the central nervous system: dizziness, noise in the head, headache.
Allergic reactions: skin rash, urticaria.
Other: weakness, sensation of stuffy ear, arthritis, myalgia, rhinitis.
When using the drug in therapeutic doses, side effects are usually mild and transient.
Drug Interaction
With the simultaneous use of Courant with anticoagulants or acetylsalicylic acid, the antithrombotic effect of the latter is increased and the risk of hemorrhagic complications is increased accordingly.
With simultaneous use, Courantil enhances the effect of antihypertensive drugs.
When used together, Courantil may reduce the anticholinergic effects of cholinesterase inhibitors.
When used concurrently, xanthine derivatives attenuate the vasodilator action of Courantil.
Overdose
Symptoms: decreased blood pressure, angina, tachycardia, hot flashes, weakness and dizziness.
Treatment: artificial vomiting, gastric lavage, appointment of activated charcoal. The vasoconstrictive action of the drug can be stopped slowly (50-100 mg / min) in / in the introduction of aminophylline. If angina symptoms persist, the administration of nitroglycerin is sublingual.
Storage conditions
Store in a dark place, out of the reach of children, at a temperature not exceeding 30 ° C.
Expiration
3 years.
Deystvuyuschee substances
dipyridamole
dosage form
dosage form
tablets
Berlin-Chemie / Menarini Germany
