Description
Latin name
DROTAVERINE
Packing
10 ampoules of 2 ml.
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Indications
spasm of smooth muscles of internal organs (cardio- and pylorospasm),
chronic gastroduodenitis,
gastric and duodenal ulcer,
gallstone disease (hepatic colitis, cholecystitis, cholecystitis, cholecystitis
hypermotor biliary dyskinesia,
spastic intestinal dyskinesia,
intestinal colic due to gas retention after surgery,
colitis,
proctitis,
tenesmus,
flatulence,
urolithiasis, vertebral cortex and peripheral arteries, the need to weaken uterine contractions and relieve cervical spasm during childbirth,
smooth muscle spasm during instrumental interventions,
dysmenorrhea,
strong labor pains.
Drotaverinum hydrochloride can also be used as an adjunct in hypertensive crises.
Contraindications
hypersensitivity to the active substance (drotaverine hydrochloride) or to any of the auxiliary components of
severe hepatic or renal failure,
severe heart failure (low cardiac output syndrome),
AV block II and III degree,
cardiogenic shock,
arterial hypotension,
children under 12 years of age.
Use during pregnancy and lactation
Use with caution in pregnancy and lactation (breastfeeding).
Composition
1 ml injection contains 20 mg drotaverine hydrochloride.
Dosage and administration of
The drug is intended for intramuscular, subcutaneous, intravenous administration.
Adults and children over 12 years of age, the average daily dose is 40-240 mg, divided into 1-3 intramuscular or subcutaneous injection of 2-4 ml of 2% solution.
In acute hepatic and / or hepatic colic, the drug is administered slowly intravenously in doses of 40-80 mg (2-4 ml of a 2% solution).
In case of peripheral circulation disorders (obliterating endarteritis, Raynaud’s disease) intra-arterial administration is allowed (slowly!).
To shorten the opening phase of the cervix during physiological delivery at the beginning of the stretching period of drotaverine, the hydrochloride is administered intramuscularly in a dose of 40 mg once, with an unsatisfactory effect, it is repeated, once, for 2 hours.
Side effects
dizziness,
palpitations,
decrease in blood pressure,
sensation of heat,
sweating,
allergic skin reactions.
Drug Interaction
Increases the effect of other antispasmodics (including M-cholin blockers), hypotension caused by tricyclic antidepressants, quinidine, procainamide.
Reduces spasmogenic morphine activity, antiparkinsonian properties of levodopa (tremor and rigidity increase).
Reliability of the spasm elimination increases phenobarbital.
Overdose
Symptoms: collapse, atrioventricular blockade, cardiac arrest, respiratory center paralysis.
Treatment: symptomatic therapy (no specific antidote).
Storage conditions
In a dry, dark place at a temperature of no higher than 25 ° C.
Expiration
3 years.
Deystvuyuschee substances
Drotaverine
Terms
pharmacy leave with prescription
Possible product names
DROTAVERIN RR D / IN 20MG / ML AMP 2ML No. 10
DROTAVERIN 0.02 / ML 2ML N10 AMP
Drotaverin 20mg / ml solution for injection 2ml Amp. t / s X10 (R)
Drotaverin ampoules 20 mg / ml 2 ml, 10 pcs.
DROTAVERIN G / HL RR D / IN. 2% 2ML No. 10
Deco Company, Russia
