Description
Latin name
Locoid
Release form
Cream for external use.
30 g
packing 30 g
30 g srdlfp40 3040 srdlfpf packing 30 srdlfpf 3065 srdlfp30 packing
Pharmacological action
Lokoid – corticosteroids, has anti-inflammatory and anti-allergic effects. It inhibits the release of cytokines (interleukins and interferon) from lymphocytes and macrophages, inhibits the release of inflammatory mediators by eosinophils, and reduces the metabolism of arachidonic acid and Pg synthesis. By stimulating steroid receptors, it induces the formation of lipocortin. Reduces inflammatory cellular infiltrates, reduces the migration of leukocytes and lymphocytes to the area of inflammation. When prescribed in recommended doses, it does not suppress the hypothalamic-pituitary-adrenal system.
Indications
Eczema dermatitis (allergic and simple), atopic dermatitis, diffuse neurodermatitis, erythroderma pruritus psoriasis, lichen planus, anogenital pruritus, insect bites, photodermatoses.
Contraindications
Hypersensitivity, post-vaccination period, bacterial, viral and fungal skin diseases (pyoderma, mycosis), skin tuberculosis, violation of the integrity of the skin (ulcers, wounds), syphilitic skin lesions, skin tumors, children (up to 2 years, with itching in the anus – up to 12 years). Rosacea, acne vulgaris, perioral dermatitis. Caution. Pregnancy (I trimester), diabetes mellitus, tuberculosis (systemic lesion), lactation.
Special instructions
Avoid contact with ointment in the eyes. For children under 12 years of age, the drug is prescribed only under strict medical supervision. If, after 7 days of use, there is no improvement or deterioration is observed, as well as in the case of the resumption of symptoms a few days after withdrawal, the use of the drug should be discontinued and consult a doctor. You should not use the drug without consulting a doctor in cases where itching in the genital area of ² ¹ ² ¹women is accompanied by vaginal discharge. With prolonged treatment and / or application to large surfaces, it is recommended to prescribe a diet with a restriction of Na + and a high content of K + to introduce a sufficient amount of protein into the body. It is necessary to control blood pressure, the concentration of glucose and cortisol in the blood, blood coagulation, diuresis, body weight of the patient.
Composition
1 g contains hydrocortisone 17-butyrate 1 mg,
excipients: liquid paraffin – 180 mg, white soft paraffin – 420 mg, cetostearyl alcohol – 60 mg, cetomacrogol 25 – 30 mg, propyl parahydroxybenzoate – 0.5 mg, benzyl alcohol – 5 mg, anhydrous citric acid – 1.8 mg, anhydrous sodium citrate – 1.2 mg, purified water – 300.5 mg.
Dosage and administration
Locoid is applied topically. The affected surface of the skin is lubricated with a thin layer no more than 3-4 times a day. The course of treatment is 1-3 weeks. The dose of the drug used within 1 week should not exceed 30-60 g. In case of itching in the anus, before applying the drug, wash the affected area with warm water and soap, then with water and dry the surface of the skin with a towel or napkin. For weeping skin diseases, lesions of the scalp, lotion and emulsion for external use are used.
Side effects
Local reactions: skin irritation in rare cases – other local reactions characteristic of corticosteroids therapy.
Systemic reactions: with prolonged use, application to large surfaces and / or use of occlusive dressings, side effects characteristic of systemic corticosteroids can be observed. The risk of local and systemic side effects when using Lokoid Lipocrem ® is lower than when using fluorinated steroids.
Storage conditions
The drug should be stored out of the reach of children at a temperature not exceeding 25 ° C.
Expiration
2 years.
Active ingredient
Hydrocortisone
Form of Treatment
cream
Appointment
For adults, For children, Pregnant doctor’s appointment, Breastfeeding mothers by appointment32 For children over 6 months, Pregnant doctor prescribing
Indications
Eczema, Urticaria, Psoriasis, Psoriitis, Neurodroma, Neurodroma Indications
Possible product names
LOCOID LIPOCREME 0.1% 30.0 CREAM
LOCOID LIPOCREME 0.1% 30G
LOCOID LIPOCREME 0.1% 30G. CREAM
Lokoid lipocream 0.1% cream for external approx. 30g Tube M (R)
LOCOID LIPOCREME CREAM 0.1% 30G
Astellas Pharma Europe B.V. BV, Netherlands
