Description
Release form
Tablets
Packing
50 pcs.
Pharmacological action
Cholagogue. Increases the formation and secretion of bile. It has a selective antispasmodic effect on the bile ducts and sphincter of Oddi. The drug does not reduce gastrointestinal motility and blood pressure.
Reduces stagnation of bile, prevents the crystallization of cholesterol and, thereby, the development of cholelithiasis.
Pharmacokinetics
Absorption and distribution of
After oral administration, it is rapidly absorbed from the digestive tract. Cmax in the blood after oral administration is achieved after 2-3 hours. It weakly binds to plasma proteins.
Excretion of
T1 / 2 is about 1 hour. Excreted in the urine: about 93% as glucuronate, 1.4% as sulfonate, 0.3% unchanged.
Indications
biliary dyskinesia and sphincter of Oddi for hyperkinetic type
non-calculous chronic cholecystitis, cholangitis, cholelithiasis
condition after surgery on the gall bladder and bile ducts, gout, yellowing, and appetite.
Contraindications
hypersensitivity
biliary obstruction
renal / hepatic insufficiency
ulcerative colitis, Crohn’s disease
gastric ulcer and duodenal ulcer
hemophilia 18 years of age.
Use during pregnancy and lactation
There is no data on the safety of the use of gimecromon during pregnancy and lactation.
Prescribing Odeston during pregnancy and lactation (breastfeeding) is permissible only in cases where the intended benefits to the mother outweigh the potential risk to the fetus or child.
Special instructions
Special precautions for disposal of unused drug
Do not dispose of drugs in the sewer or in your household waste containers. You should contact your pharmacist about how to dispose of an unused product. These activities will help protect the environment.
Effect on the ability to drive vehicles and control mechanisms
The drug does not affect the ability to drive vehicles and engage in other potentially dangerous activities that require increased concentration and speed of psychomotor reactions.
Composition
1 tab. contains:
Active substances: gimekromon 200 mg
Excipients: potato starch – 45 mg, gelatin – 3 mg, sodium lauryl sulfate – 1 mg, magnesium stearate – 1 mg.
Method approx Do not take a double dose of the drug in order to compensate for the missed.
Side effects of the
From the digestive system: diarrhea, flatulence, abdominal pain, ulceration of the gastrointestinal mucosa.
Other: allergic reactions, headache.
Drug interaction
With the simultaneous use of morphine, which causes spasm of the sphincter of Oddi, weakens the effect of Odeston.
With the simultaneous use of Odeston with metoclopramide, a mutual weakening of action is noted.
Odeston enhances the effects of indirect anticoagulants.
Overdose
There have been no reports of an overdose of Odeton at this time.
Storage Conditions
In a dark place at a temperature not exceeding 25 ° C.
Shelf life
3 years.
Active ingredient
Gimekromon
Conditions for dispensing from pharmacies
Without a prescription
dosage form
tablets
Possible product names
ODESTON 0.2 N50 TABLE
Odeston 200mg Tab. X20
Odeston 200mg Tab. X50
Odeston 200mg tablet X50 Blist. (ACTION 10)
Odeston 200mg tab. X50 Blist. (ACTION)
