Description
Pharmacological action
NEXT ACTIVGEL is a combination of two active substances – ibuprofen and levomenthol.
Ibuprofen is a non-steroidal anti-inflammatory drug derived from propionic acid that indiscriminately blocks the enzymes cyclooxygenase 1 (COX-1) and cyclooxygenase 2 (COX-2), as a result of which it inhibits the synthesis of prostaglandins – mediators of pain, inflammation and hyperthermia.
When applied topically, ibuprofen has an analgesic and anti-inflammatory effect.
Levomenthol has a local irritant effect, which leads to the rapid development of the analgesic effect of the drug.
The combination of ibuprofen and levomenthol reduces pain and inflammation, is effective for joint pain when moving and at rest, and reduces morning stiffness of the joints.
Indications
As a local anesthetic and anti-inflammatory agent for conditions such as muscle pain, back pain, arthritis, pain in ligament injuries and sprains, sports injuries and neuralgia.
Contraindications
hypersensitivity to ibuprofen or other components of the drug
hypersensitivity to acetylsalicylic acid and other NSAIDs
complete or incomplete combination of bronchial asthma, recurrent nasal polyposis and paranasal sinuses and other paranasal sinuses and other sinuses
violation of the integrity of the skin at the site of application of the drug (including infected wounds and abrasions, weeping dermatitis, eczema)
children up to 14 years
pregnancy, lactation.
With caution
Before using the drug, you should consult a doctor in the presence of concomitant diseases of the liver and kidneys, gastrointestinal tract, exacerbation of hepatic porphyria, with bronchial asthma, urticaria, rhinitis, polyps of the nasal mucosa, chronic heart failure, as well as elderly patients.
Special instructions
Avoid contact with eyes, lips and other mucous membranes, damaged skin.
After application to the skin, do not apply an occlusive (hermetic) dressing.
Avoid exposure to sunlight on the area of application of the drug.
With prolonged use of a large amount of the drug, there is a risk of developing systemic side effects.
Before using the drug, consult your doctor if you have kidney disease.
Composition of
1 g of gel contains:
ibuprofen – 50 mg,
levomenthol – 30 mg.
Excipients:
propylene glycol – 100 mg,
ethanol 95% – 300 mg,
carbomer – 20 mg,
diisopropanolamine – 55 mg,
purified water – up to 1000 mg.
Dosage and administration
The drug is intended for external use.
Adults and children from 14 years of age, a small amount of gel (strip 3-5 cm long) is applied with a thin layer on the skin over the lesion and rubbed with light movements.
Immediately after using the drug, wash your hands if they are not the object of treatment.
Re-use of the drug is possible no earlier than 4 hours. The drug can be applied up to 4 times in 24 hours.
The duration of use of the drug without consulting a doctor is no more than 10 days.
If you need longer use, consult your doctor.
Side effects
The frequency of adverse reactions was estimated based on the following criteria: very often ( 1/10), often ( 1/100 to <1/10), infrequently ( 1/1000 to <1 / 100), rarely (from 1/10 000 to <1/1000), very rarely (> 1/10 000), the frequency is unknown (the frequency cannot be determined based on available data).
– Immune system disorders
Frequency unknown: hypersensitivity reactions (nonspecific allergic reactions and anaphylactic reactions), reactions from the respiratory tract (bronchial asthma, including exacerbation, bronchospasm, shortness of breath, dyspnea), skin reactions (itching , urticaria, purpura, exfoliative and bullous dermatoses, including toxic epidermal necrolysis (Lyell syndrome), Stevens-Johnson syndrome, erythema multiforme, eczema, photosensitivity), Quincke edema.
– Disorders of the gastrointestinal tract
Frequency unknown: abdominal pain, dyspepsia.
– Disorders of the kidneys and urinary tract
Frequency unknown: impaired renal function.
With prolonged use, systemic side effects of NSAIDs may develop.
If side effects occur, discontinue use of the drug and consult a doctor.
Overdose
The effects of overdose with external use of the drug are not described.
If you take the drug inside, you may experience headache, vomiting, drowsiness, lowering blood pressure.
Recommended gastric lavage (only within an hour after ingestion), intake of activated carbon, alkaline drink, forced diuresis, symptomatic therapy.
Storage conditions
At a temperature not exceeding 25 ° C.
Keep out of the reach of children.
Expiration
2 years.
Do not use after the expiration date printed on the package.
Deystvuyuschee substances
Ibuprofen , Levomentol
Dosage form
gel for external use
