Description
Pharmacological action
HerpferonВ®, an ointment for topical and external use, is a combined drug with anti-inflammatory, anti-inflammatory, anti-inflammatory and anti-inflammatory drugs.
Interferon alpha-2b human recombinant has a pronounced antiviral activity (inhibits virus replication in infected cells) and an immunomodulatory effect (increased phagocytic activity of macrophages in the lesion foci).
Acyclovir has a pronounced antiviral effect. Highly active against type 1 and type 2 Herpes simplex virus and varicella zoster virus (Varicella zoster).
Lidocaine has a local anesthetic and moderate antipruritic effect.
The combination of active ingredients provides a more pronounced antiherpetic effect: it prevents the formation of new elements of the rash, reduces the likelihood of skin dissemination, accelerates healing, and reduces pain.
Pharmacokinetics
When applying the ointment, systemic absorption is low: with intact skin, absorption is minimal, in blood and urine is not determined, with affected skin – absorption is moderate.
Indications
Primary and recurrent herpes of the skin and mucous membranes (including genital herpes), herpes zoster.
Contraindications
Hypersensitivity.
Composition
Active ingredients: interferon alfa-2b human recombinant at least 20,000 IU acyclovir 30 mg lidocaine hydrochloride 10 mg
Excipients: methyl parahydroxybenzoate – 2 mg macrogol 1500 – 290 mg macrogol 400 – 660 mg.
Dosage and administration
Topically, externally.
The preparation GerpferonВ® is applied to the affected areas of the skin and mucous membranes with a thin layer 5 times a day with an interval of 4 hours. The duration of treatment is 5-10 days.
Side effects
Perhaps peeling of the skin at the site of prolonged application of the ointment.
dosage form
Ointment
Indications
Herpes, Genital herpes, Shingles
