Description
Release form
Lyophilized powder for oral administration
Packing
6 pcs.
Pharmacological action
Reaferon-EU-Lipint the world’s only oral interferon-alpha-2. Interferon in its pure form cannot be taken orally, since it easily decomposes under the action of enzymes in the stomach. Reaferon-EU-Lipint is enclosed in liposomes, which protect it from destruction in the body.
Reaferon-EU-Lipint enters the body in the most natural way – through the mouth. Non-traumatic administration of the drug is very important in the treatment of children. Provides a long stay of interferon in the blood. The liposome membrane is resistant to the aggressive environment of the stomach and gastrointestinal tract. The interferon enclosed in the liposome almost completely passes through the digestive tract, enters the liver, is absorbed into the blood there, and begins to slowly, gradually released. When taking Lipint, the content of its own interferon in the body is 100% higher than when injecting Reaferon-EC. It is most suitable for emergency prevention of colds and flu. Prophylactic use of Lipint more than 2 times reduces the likelihood of illness. There is no risk of transmitting dangerous viral infections with the needle (AIDS, hepatitis).
Reaferon-EU Lipinta contains antioxidants – vitamins E and C. It has been established that the use of interferon together with vitamins E and C enhances the antiviral effect of interferon by 14 times. With the combined use of interferon and antioxidants (vitamins E and C) in the treatment of children, the toxic effect of IFN on a growing body is neutralized.
It has antiviral, immunomodulating and antitumor activity.
Indications
Reaferon is used for viral and tumor diseases.
The drug is effective in viral hepatitis. Assign to adults in the treatment of acute viral hepatitis B. The drug is most effective at the beginning of the icteric period until the 5th day of illness. With developed hepatic coma and cholestatic hepatitis, the drug is not very effective.
Used for viral conjunctivitis, keratoconjunctivitis, keratitis, uveitis, as well as with hairy cell leukemia, chronic myeloid leukemia, kidney cancer. There is also evidence of the use of reaferon in the treatment of multiple sclerosis.
Contraindications
Allergic diseases, pregnancy (insufficient number of observations). In patients with cardiovascular disease, hemodynamic control is necessary (periodic ECG recording). Individual intolerance to interferons.
Special instructions
Like all interferons, in individuals with prolonged use, the drug can cause antibodies to interferon, which leads to a decrease in the therapeutic effect. The use of the drug for viral hepatitis B at a later date is less effective. Not effective in developing hepatic coma and cholestatic disease. In patients with the erythrodermic stage of fungoid mycosis, when the temperature rises above 39 ° C, and in case of exacerbation of the process, administration of Reaferon-EC should be discontinued. In individuals with a high pyrogenic reaction (39 degrees C and above), the simultaneous use of indomethacin is recommended for the introduction of Reaferon-EC. In case of storage of the solution for topical use, it is necessary, observing the rules of asepsis and antiseptics, transfer the contents of the ampoule to a sterile vial and store the solution in the refrigerator at 4-10 degrees C. With no more than 12 hours. In case of development of leuko- and thrombocytopenia, a blood test is necessary 2-3 times a week.
Composition of
1 vial with lyophilisate for preparation of a solution for intramuscular administration contains:
active substance: extract of prostate tissue of gobies that have reached puberty 5 mg mg and vitamin C 1, 5 mg /
Dosage and administration of
REAFERON-EU-LIPINT is taken orally, 30 minutes before meals. Immediately before use, add 1-2 ml of distilled or chilled boiled water to the contents of the vial. When shaking for 1-5 minutes, a uniform white suspension should form.
Acute hepatitis B: for adults and schoolchildren – 1 million IU 2 times a day, for children 3-7 years old – 0.5 million IU 1 time per day for 10 days, if necessary (after control biochemical blood tests) and more, until complete recovery.
Chronic hepatitis B (in active and inactive replicative forms associated with glomerulonephritis): schoolchildren and adults – 1 million IU, children 3-7 years old – 0.5 million IU for 10 days 2 times a day and then for 1 month every other day 1 time per day at night.
Side effects of
When using reaferon, chills, general malaise, fever, skin allergic reactions (rash, itching), leuko- and thrombocytopenia are possible. With pronounced side effects, the injection is stopped.
Storage conditions
At a temperature of + 4 C to + 10 C.
active substance
Interferon alfa-2b
Terms and conditions
prescription
lekarstvennaja form
Solution for
Indications
Chlamydia, Allergic conjunctivitis, the prevention of influenza, allergic rhinitis, hepatitis, influenza, tick-borne encephalitis, SARS
NGO Vector, Russia
