Description
Latin name
Irunin
packaging 10 pcs
Contraindications
Hypersensitivity to the components of the drug, pregnancy (I trimester)
Use during pregnancy and lactation
Women of childbearing age who take Irunin need to use adequate methods of contraception throughout the course of treatment until the onset of the first menstruation after its completion.
Pregnant women in the II and III trimester Irunin should be prescribed only if the expected benefit to the woman outweighs the potential risk to the fetus.
Since a small amount of itraconazole is excreted in breast milk, the expected benefits of taking itraconazole must be weighed against the risk to the baby during breastfeeding.
In case of doubt, the issue of terminating breastfeeding should be resolved.
Composition
1 capsule contains:
Active ingredient:
itraconazole
Excipients:
sucrose,
starch,
hydroxypropyl methylcellulose
.
Dosage and administration
The drug Irunin is prescribed inside immediately after a meal, the capsules are swallowed whole.
With vaginal candidiasis, the drug is prescribed at a dose of 200 mg 2 times a day for 1 day or at a dose of 200 mg 1 time per day for 3 days.
With fungal skin diseases – 100 mg once a day for 15 days.
With candidiasis of the oral cavity – 100 mg 1 time per day for 15 days.
For fungal diseases of the nails, Irunin is prescribed at a dose of 200 mg / day for 3 months or repeat courses of 200 mg 2 times a day for 1 week with subsequent interruptions (pulse therapy).
In case of fungal diseases of internal organs – 200 mg once a day for 2-7 months, if necessary, increase the dose of Irunin to 200 mg 2 times a day.
Side effects
Rarely – itching, burning sensation in the vagina, skin rash in the genital area, not requiring drug withdrawal.
Drug interaction
Strengthens and lengthens the effect of drugs metabolized by enzymes such as cytochrome P450 (isoenzyme CYP3A4): terfenadine, astemizole, cisapride midazolam, triazolam (indirect), medication, medication such as dihydropyridine, quinidine, tacrolimus and vincristine.
Inhibitors of the CYP3A4 isoenzyme (ritonavir, indinavir, clarithromycin) increase bioavailability.
Inductors of microsomal oxidation in the liver (rifampicin, isoniazid, phenytoin) reduce bioavailability.
Antacid drugs, m-anticholinergics, H2-histamine receptor blockers, omeprazole and sucralfate reduce absorption (the interval between doses should be at least 2 hours).
When combined with cisapride, the toxicity of the latter increases with the development of ventricular arrhythmia.
Storage Conditions
In a dry, dark place at a temperature not exceeding 25 ° C.
Expiration
2 years.
prescription drugstore vacations from
pharmacies Prescription
lekarstvennaja form
kapsul
Prescribing
Pregnant as prescribed by a doctor, Adults prescribed by a doctor
Indications
Indications
from yeast
