Description
Latin name
FASTUM ®
Release form
Gel for external use 2.5%.
Packing
30 g in a tube.
Pharmacological action
Pharmacodynamics
NSAIDs for external use. The mechanism of action is associated with inhibition of prostaglandin synthesis. It has a local analgesic, anti-inflammatory, antiexudative effect.
In the symptomatic treatment of diseases of the joints, tendons, ligaments, muscles, skin with the joint syndrome, it reduces joint pain at rest and during movement, morning stiffness and swelling of the joints.
Pharmacokinetics
When applied topically, it is absorbed extremely slowly. Bioavailability is 5%. When used in a dose of 50-150 mg, the concentration in the blood plasma is 0.08-0.15 μg / ml. Does not cumulate in the body.
Indications
Diseases of the musculoskeletal system (joint syndrome with exacerbation of gout, rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, osteoarthritis, osteochondrosis with radicular syndrome, inflammatory lesions of the ligaments, rheumatoid arthritis)
post-traumatic inflammation of the soft tissues and musculoskeletal system.
Contraindications
Soaking dermatoses, eczema, infected abrasions, wounds
history of bronchospasm, urticaria or rhinitis due to the use of acetylsalicylic acid
child age up to 12 years of pregnancy
pregnancy acetylsalicylic acid and other NSAIDs.
Use with caution in: erosive and ulcerative lesions of the gastrointestinal tract, severe impaired renal and hepatic function, chronic heart failure, bronchial asthma, and liver porphyria.
Use during pregnancy and lactation
The drug is contraindicated for use in the III trimester of pregnancy and during lactation (breastfeeding).
In the first and second trimesters, the drug is used with caution.
Composition of
100 g of gel contain:
Active substances:
ketoprofen 2.5 g.
Excipients:
carbomer 940 – 1.5 g,
ethanol 96% – 40 ml,
neroli oil – 0.05 g,
lavender oil (hybrid lavender oil.
Dosage and administration
The drug is intended for external use.
A small amount of gel (3-5 cm long column) is applied 1-2 times / day with a thin layer on the skin over the site of inflammation and rubbed lightly.
The duration of treatment should not exceed 14 days.
Side effects
Local reactions: allergic dermatitis, eczema, flushing of the skin, photodermatitis, bullous dermatitis, exanthema, purpura.
Systemic reactions: urticaria, generalized skin rash, edema, photosensitivity, stomatitis.
Drug Interaction
The interaction of Fastum with other medicines has not been described.
overdose
Due to extremely low systemic absorption, overdose is unlikely.
Storage conditions
Store in a dark place and out of the reach of children at a temperature of 15 ° to 25 ° C.
Expiration
5 years.
The active substance
Ketoprof en
Terms of delivery from pharmacies
Without a prescription
Dosage form
Dosage form
gel for external use
Berlin-Chemie / Menarini Germany
