Description
Release form
Sublingual tablets.
Packing
10 pcs.
Pharmacological action
Combined immunostimulating drug of bacterial origin for sublingual (sublingual) administration. It is a multivalent antigenic complex, including bacterial lysates – the most common respiratory infections. The lysates that make up Ismigen ® are obtained by mechanical destruction of bacterial cells. Ismigen ® has a non-specific immunostimulating and specific vaccinating effect.
Ismigen ® sublingual tablets has an effect on various parts of the immune system. It stimulates both local (increases the concentration of secretory IgA) and systemic (cellular and humoral) immunity. It activates phagocytosis, increases the content of lysozyme in saliva, promotes an increase in the number of immunocompetent cells, increases the concentration of serum IgA, IgG, IgM and reduces the concentration of serum IgE.
Increases the functional activity of macrophages (including alveolar) and polymorphonuclear leukocytes, which contributes to the destruction of infectious agents. As a result of treatment with Ismigen ®, the frequency, severity and duration of acute respiratory tract infections are reduced and symptoms such as fever, cough, shortness of breath, and the need for antibacterial and anti-inflammatory therapy in patients with chronic diseases of the respiratory tract decreases and the drug also prevents exacerbations.
Indications
Acute and subacute infections of the upper and lower respiratory tract: bronchitis, tonsillitis, pharyngitis, laryngitis, rhinitis, sinusitis, otitis media, including complications after the flu (treatment as part of combination therapy).
Recurrent upper and lower respiratory tract infections, chronic bronchitis (prevention of exacerbations).
Contraindications
Hypersensitivity to the active and / or auxiliary components of the drug
pregnancy and lactation
children under 3 years of age.
Use during pregnancy and lactation
Contraindicated in pregnancy and lactation.
Special instructions
Children aged 3 to 6 years should be monitored by adults during the administration of each dose until the tablets are completely dissolved in the oral cavity.
Influence on the ability to drive vehicles and other mechanisms requiring increased concentration of attention
Not affected.
Composition of
Lyophilized bacterial lysates – 50 mg, including the active component: bacterial lysates Staphylococcus aureus, Streptococcus E1 / Tococidae Tococcus pyogenes, Streptococcus yococcus viridis, Tococida yocidae Tiridae, , TY3 / EQ14, TY5 / EQ15, TY8 / EQ23, TY47 / EQ 24), Klebsiella pneumoniae, Klebsiella ozaenae, Haemophilus influenzae b, Neisseria catarrhalis – 7.0 mg
excipient: glycine – 43 mg. Excipients – microcrystalline cellulose 150.0 mg, calcium hydrogen phosphate dihydrate 35.0 mg, colloidal silicon dioxide 10.0 mg, magnesium stearate 3.0 mg, ammonium glycyrrhizinate 1.2 mg, mint flavor 0.8 mg.
Dosage and administration
Take under the tongue on an empty stomach. The tablet should be kept under the tongue until completely dissolved. Sublingual tablets should not be absorbed, chewed or swallowed.
Acute and subacute infections of the upper and lower respiratory tract – 1 tablet per day until the symptoms disappear (at least 10 days).
Recurrent infections of the upper and lower respiratory tract, prevention of exacerbations of chronic respiratory diseases – 1 tablet per day for 10 days.
The preventative course includes three cycles of 10 days with 20-day intervals between them. The preventive course should be carried out no more than 1-2 times a year.
If you skip the next dose, you should not double it at the next dose.
Side effects
The incidence of side effects is classified according to the recommendations of the World Health Organization:
very often – more than 10%
often – more than 1 and less than 10%
rarely – more than 0.1 and less than 1%
rarely – more than 0.01 and less than 0.1%
is very rare – less than 0.01%.
From the skin: very rarely – urticaria, impetiginous dermatitis, folliculitis.
Other: very rare – inflammation of the salivary gland, acute laryngitis, rhinitis.
Drug Interactions
Ismigen may be used concurrently with drco-drugs intended for the treatment of acute and chronic respiratory diseases.
Features of the interaction of Ismigen with other drugs have not yet been described.
Overdose
No case of overdose is available.
Storage Conditions
Do not store above 25 ° C.
Keep out of the reach and sight of children.
Shelf life
3 years.
Deystvuyushtee substance
Lizat bacteria
dosage form
lozenges
Possible product names
ISMIGEN 0.007 N10 TABLE SINGLING
ISMIGEN TAB. GINGER 7MG No. 10
ISMIGEN TAB. Sublingual 7mg No. 10
Ismigen sublingual tablets 7 mg, 10 pcs.
Bruskettini, Italy
