Description
Latin name
SERUM AGAINST OREFI NEREFRENEFRENEFRENEFRENEFRENEFRENEFRENEFRENEFRENEFRENEFRENEFENEFIREFEREDENEFRENEFREDERENEFREDERENEREDERENT
Magnerot
Release form
Tablets.
Packaging
Per pack 50 pcs.
Pharmacological action
Magnerot – a preparation of magnesium. Magnesium is a macrocell, it is necessary for providing many energy processes, it is involved in the metabolism of proteins, fats, carbohydrates and nucleic acids. Magnesium takes part in the process of neuromuscular excitation, inhibiting neuromuscular transmission. Of particular interest is magnesium as a natural physiological calcium antagonist.
Magnesium controls the normal functioning of myocardial cells, is involved in the regulation of myocardial contractile function. In stressful situations, an increased amount of free ionized magnesium is excreted, and therefore an additional amount of magnesium contributes to an increase in resistance to stress.
Magnesium deficiency leads to neuromuscular disorders (motor and sensory hyperactivity, convulsions, paresthesia), mental changes (depression, confusion and hallucinations), cardiovascular diseases (ventricular extrasystole, tachycardia, and increased sensitivity to cardiac glycosides).
Magnesium deficiency during pregnancy increases the likelihood of toxicosis and premature birth. Salts of orotic acid are involved in the metabolism. In addition, salts of orotic acid are necessary for the fixation of magnesium on ATP in the cell and the manifestation of its action.
Pharmacokinetics
Absorbed approximately 35 40% of the dose taken. Hypomagnesemia stimulates the absorption of magnesium ions. The presence of orotic acid salts improves the absorption of magnesium. Magnesium is excreted by the kidneys, excretion decreases with a deficiency of magnesium and increases with its excess.
Indications
myocardial infarction
angina pectoris
chronic heart failure
cardiac arrhythmias caused by magnesium deficiency
spastic conditions – pain and muscle spasms (including angiospasm)
atherosclerosis lipid arteriosclerosis lipid arteriosclerosis erythematosis
Contraindications
hypersensitivity to the components of the drug
impaired renal function
urolithiasis
predisposition to the formation of calcium-magnesium-ammonium-phosphate stones
lactobacillus malignancy 18 .
Use during pregnancy and lactation
It is possible to use the drug during pregnancy and lactation (breastfeeding) according to indications, since during these periods the need for magnesium increases significantly. If its content is not balanced, then this can lead to serious complications, including miscarriage.
Use of the drug during pregnancy and lactation is possible if the potential benefit to the mother outweighs the potential risk to the fetus and baby.
Ingredients
Active ingredient mgdrgp colloidal silicon dioxide – 2.5 mg carmellose sodium – 10 mg MCC – 67.5 mg corn starch – 22.5 mg povidone K30 – 30 mg lactose monohydrate – 50 mg sodium cyclamate – 1.5 mg talc – 18.75 mg magnesium stearate – 1.63 mg
Dosage and administration
Inside, before meals, with a small amount of liquid.
Assign 2 tablets 3 times a day for 7 days, then 1 tablet 2-3 times a day daily. The duration of the course is at least 4-6 weeks. If necessary, Magnerot ® can be used for a long time.
For night cramps of the calf muscles, it is recommended to take 2-3 tablets in the evening.
Side effects
From the gastrointestinal tract: unstable stool and diarrhea (when taking high doses), which usually go away on their own with a lower dose.
Allergic reactions.
If any of these side effects worsen or any other side effects that are not listed in the instructions appear, you should inform your doctor.
Overdose
Symptoms: decreased blood pressure, nausea, vomiting, depression, slowing reflexes, respiratory depression, coma, cardiac arrest, anuric syndrome.
Treatment: rehydration, forced diuresis. Renal insufficiency requires hemodialysis or peritoneal dialysis.
Storage conditions
At a temperature not exceeding 25 ° C.
term life
5 Chron
Dispensing conditions from
pharmacies Without a prescription
dosage form
dosage form
tablets
Crest Pharma Lek, Germany
