Description
Latin name
MAGNESIUM SULFATE
Dosage form
Solution for intravenous administration
Packing
5 ml – ampoules (10) – packs of cardboard.
Pharmacological action
Pharmacological action – sedative, antispasmodic.
Pharmacodynamics
When administered parenterally, it has a depressing effect on the central nervous system. Depending on the dose, a sedative, hypnotic or anesthetic effect may be observed. Magnesium sulfate has a depressing effect on neuromuscular transmission.
Reduces the excitability of the respiratory center, in large doses with parenteral administration, can cause respiratory paralysis.
Lowers blood pressure, incl. in connection with the general calming effect (the effect is more pronounced with hypertension). Magnesium sulfate is excreted by the kidneys, in the process of excretion, diuresis is enhanced.
Magnesium ion antagonists are calcium ions. A decrease in calcium in the blood is accompanied by an increase in the action of magnesium.
Indications
hypertensive crisis
late toxicosis pregnant
convulsive syndrome.
relief of epileptic status (as part of complex therapy).
Contraindications
hypersensitivity to the drug
AV block
arterial hypotension
condition, accompanied by calcium deficiency, depression of the respiratory center.
Composition
Solution for iv administration 1 ml
magnesium sulfate 250 mg
Dosage and administration of
i / m or iv. Magnesium sulfate is used only as directed by a doctor. Doses are specified taking into account the therapeutic effect and the concentration of magnesium sulfate in the blood serum.
In case of hypertensive crises, they are injected IM or IV slowly, 520 ml of a 25% solution. In convulsive syndrome, spastic conditions, the drug is prescribed IM 520 ml of a 25% solution in combination with anxiolytic drugs with a pronounced central muscle relaxant effect.
For acute poisoning with mercury, arsenic, 510 ml of a 510% solution of magnesium sulfate are injected iv with tetraethyl lead.
Overdose
Symptoms: respiratory depression, depression of the central nervous system, up to the development of anesthesia.
Treatment: as an antidote for an overdose of magnesium sulfate, calcium preparations are used – calcium chloride or calcium gluconate.
Storage conditions
At a temperature not exceeding 30 ° C.
Keep out of the reach of children.
Expiration
3 years.
Do not use after the expiration date printed on the package.
Deystvuyuschee substances
magnesium sulfate
Terms and conditions
prescription
Dosage form
infusion solution
Groteks Ltd., Russia
