Description
Latin name
Melaxen
release form
tablets
Packaging
in a blister pack of 12 tablets
Pharmacological action
Melaxen – an adaptogenic drug, chemical analogue of the biogenic amine melatonin.
Synthesized from amino acids of plant origin. The chemical formula is N-acetyl-5-methoxytryptamine, molecular weight 232. It is soluble in water, alcohol, lipids.
Is a synthetic analogue of the hormone pineal gland. Normalizes circadian rhythms. It regulates the sleep-wake cycle, daily changes in motor activity and body temperature. It contributes to the normalization of night sleep: it accelerates falling asleep, improves sleep quality, reduces the number of night awakenings, improves well-being after morning awakening, does not cause a feeling of lethargy, weakness and fatigue upon waking, dreams become more vivid and emotionally saturated.
Adapts the body to a quick change of time zones, reduces stress reactions. It exhibits immunostimulating and pronounced antioxidant properties.
Inhibits the secretion of gonadotropins and, to a lesser extent, other hormones of the adenohypophysis (corticotropin, thyrotropin and growth hormone). Not addictive and addictive.
Indications
– As a sleeping pill.
– As an adaptogen for normalizing biological rhythms.
Contraindications
– Severe renal impairment.
– Autoimmune diseases.
– Leukemia.
– Lymphoma.
– Allergic reactions.
– Lymphogranulomatosis.
– Myeloma.
– Epilepsy.
– Diabetes mellitus.
– Chronic renal failure.
– Pregnancy.
– Lactation (breastfeeding).
– Hypersensitivity to the drug.
Use during pregnancy and lactation
The drug is contraindicated in pregnancy and lactation (breastfeeding).
Composition
1 coated tablet contains: active substance: 3 mg melatonin.
excipients: calcium phosphate disubstituted, microcrystalline cellulose, magnesium stearate, talc, pharmaceutical glaze, isopropyl alcohol.
Dosage and administration
Inside, 30 40 minutes before bedtime. Adults take 0.5 1 tablets 1 time per day. As an adaptogen when changing time zones – 1 day before the flight and in the next 2 5 days – 1 tablet per day. The maximum daily dose is up to 2 tablets per day.
Side effects
When used in physiological doses, adverse reactions rarely develop. Allergic reactions, edema (in the first week of administration), headache, nausea, vomiting, diarrhea, and morning drowsiness are described while taking melatonin.
Drug Interaction
When used concurrently, melatonin enhances the effect of CNS-depressant drugs and beta-blockers.
Not recommended for use with hormonal medicines.
Not compatible with MAO, ACS and cyclosporine inhibitors.
Overdose
Symptoms: increased severity of side effects.
Treatment: gastric lavage, symptomatic therapy.
Storage conditions
The drug should be stored in a dry, the place protected from light at a temperature from 10 ° to 30 ° C.
Expiration
4 years.
Deystvuyuschee substance
melatonin
Dosage form
Dosage form
tablets
Unipharm Inc., USA
