Description
Latin name
Metadoxil
Release form
Ampoules, 5 ml.
Packing
10 ampoules.
Indications
Comprehensive therapy of liver diseases, especially alcohol etiology acute alcohol intoxication chronic alcoholism alcohol withdrawal syndrome.
Contraindications
Hypersensitivity to any component of the drug pregnancy lactation.
Use during pregnancy and lactation
Contraindicated.
Composition
Active ingredient:
Methadoxine (pyridoxine L-2 pyrrolidone 5-carboxylate), 300 mg
Inactive ingredients:
Sodium metabisulfite sodium edetate methyl-p-hydroxybenzoate water for injection
Dosage and administration of
In acute alcohol intoxication, 300-600 mg (5-10 ml) or iv 300-900 mg (5-15 ml) are administered depending on the degree of intoxication.
With iv administration, the required dose of the drug is diluted in 500 ml of isotonic sodium chloride solution or 5% dextrose (glucose) solution and administered dropwise for 1.5 hours.
Toxic liver damage of alcoholic etiology, prevention of the formation of cirrhosis of alcoholic origin and chronic alcoholism: inside 500 mg (1 tablet) 2 (1 g /) 15-30 minutes before a meal. The dose can be increased to 500 mg 3 (1.5 g /) or injected in a dose of 300 mg (5 ml) / The course of treatment is at least 90 days.
With alcohol withdrawal syndrome iv in the form of infusion at a dose of 900 mg (15 ml) 1 time / for 3-7 days, depending on the patient’s condition.
Side effects
Possibly: an allergic reaction. In patients with bronchial asthma, bronchospasm may develop.
Drug Interactions
When used together, it reduces the effectiveness of levodopa.
Storage conditions
Store in a dark place at a temperature not exceeding 25 ° C.
Expiration
5 years.
Terms leave through pharmacies
In retseptu
lekarstvennaja form
Solution for and infusions
Laboratory Baldacci Spa, Italy
