Description
Release form
10 tablets per blister strip packaging from a film of polyvinyl chloride and varnished aluminum foil. 1, 2, 3, 4 or 5 blister packs along with instructions for use are placed in a pack of cardboard.
Pharmacological action
Combined drug whose action is due to the properties of its constituent substances. It has a sedative and antispasmodic effect, moderate cardiotonic effect (slows down the rhythm and increases the strength of heart contractions), has moderate hypotensive properties.
Ethyl bromisovalerianate has a sedative and antispasmodic effect due to irritation, mainly of the oral and nasopharyngeal receptors, a decrease in reflex excitability in the central parts of the nervous system and an increase in inhibition in the neurons of the cortex and subcortical structures of the brain, as well as a decrease in the activity of central vasomotor centers and a direct local antispasmodic effect on smooth muscles.
Motherwort herb has a pronounced sedative (calming), moderate cardiotonic (slows the rhythm and increases the strength of the heart contractions), moderate hypotensive effect.
Peppermint oil has a vasodilating reflex, antispasmodic, mild choleretic, antiseptic effect. The mechanism of action is associated with the ability to irritate the “cold” receptors of the oral mucosa and reflexively expand the vessels of the heart and brain. Eliminates the phenomena of flatulence due to irritation of the receptors of the mucous membrane of the gastrointestinal tract (GIT), increasing intestinal motility.
Indications
Sleep disorders, neurosis-like conditions accompanied by increased irritability and excitability, excitation states with pronounced autonomic manifestations as an antispasmodic, for intestinal cramps, and also as a symptomatic (soothing and vasodilating) cardiovascular system disorder.
Contraindications
– hypersensitivity to the components of the drug
– severe impaired renal and / or liver function
– erosive and ulcerative lesions of the gastrointestinal tract (acute phase)
– pregnancy
– breastfeeding period (infant) 18 efficacy and safety not established).
With caution: – impaired liver and / or kidney function
– epilepsy
– alcoholism
Patients from the high-risk group, including those with liver diseases, craniocerebral injuries, and brain diseases.
If you have one of the listed diseases / conditions, be sure to consult your doctor before taking the drug.
Special instructions
Experience with the drug in children under 18 years of age, during pregnancy and during breastfeeding is absent. Long-term use of the drug in high doses is not recommended, due to the possible toxic effect during the accumulation of bromine in the body. During the use of the drug should not drink alcohol.
Corvalol Fito drops contains 47.5% ethyl alcohol, so when taken in the maximum single dose of the drug, the content of absolute ethyl alcohol (ethanol) is 0.308 g, and in the maximum daily dose – 0.923 g.
Effect on the ability to drive vehicles and mechanisms : Due to the possibility of dizziness, decreased concentration and other side effects associated with taking the drug, during the treatment period, patients are advised to refrain from driving and engaging in other potentially dangerous activities that require an increased concentration of attention and speed of psychomotor and motor reactions.
Composition
Active substances: motherwort herb extract (motherwort extract dry) – 14.00 mg or 28.00 mg, ethyl bromisovalerianate (ethyl ester of alpha bromisovalerianic acid) – 8.20 mg or 16.40 mg, peppermint leaf oil (peppermint oil) – 0 , 58 mg or 1.16 mg.
Excipients: lactose (lactose monohydrate) – 79.21 mg or 158.42 mg, betadex (beta-cyclodextrin) – 55.55 mg or 111.10 mg, potato starch – 35.56 mg or 71.12 mg, magnesium aluminometasilicate (Neusilin UFL 2) – 4.00 mg or 8.00 mg, talc – 2.00 mg or 4.00 mg, magnesium stearate – 0.90 mg or 1.80 mg.
Dosage and administration
For oral administration, before meals, with water.
For tablets, 0.58 mg + 14.00 mg + 8.20 mg: for adults, 2 tablets 2 times a day.
For tablets, 1.16 mg + 28.00 mg + 16.40 mg: for adults, 1 tablet 2 times a day.
With tachycardia, a single dose may be increased to 3 tablets. The maximum daily dose is 6 tablets.
The course of treatment is 4 weeks (28 days). The duration of admission can be increased on the recommendation of a doctor.
Side effects of
From the immune system: allergic reactions
From the central nervous system: drowsiness, weakness, dizziness, decreased ability to concentrate
From the cardiovascular system: slowing the heart rate
From the gastrointestinal tract: dyspepsia.
These phenomena occur when the dose of the drug is reduced or the drug is discontinued. With prolonged use of high doses of the drug, it is possible to develop drug dependence, as well as accumulation of bromine in the body and the development of the phenomena of bromism, the manifestations of which are: depressed mood, apathy, rhinitis, conjunctivitis, hemorrhagic diathesis, impaired coordination of movements.
If any of the side effects indicated in the instructions are aggravated, or you notice any other side effects not listed in the instructions, inform your doctor.
Drug interaction
With the simultaneous use of the drug Corvalol Phyto with drugs that inhibit the activity of the central nervous system (sedatives, hypnotics, antipsychotics, tranquilizers), mutually reinforcing effects are possible. Enhances the action of antispasmodic, analgesic agents. Alcohol enhances the effect of the drug and its toxicity.
Overdose
Overdose is possible with frequent and prolonged use of the drug. If the recommended doses are exceeded, dose-dependent side effects may increase.
Symptoms: weakness, drowsiness, dizziness. With prolonged use, chronic bromine intoxication may occur (See section Side effects).
Treatment: symptomatic.
Active ingredient
Metamizole sodium, Pitophenone, Etylbromisovalerianate
lekarstvennaja form
tablets
