Description
Release form
Tablets.
Pharmacological action
Pharmacotherapeutic group: sedative
ATX:
Other hypnotics and sedatives
Pharmacodynamics:
Combined drug whose action is due to the properties of its constituent substances. It has a sedative and antispasmodic effect, moderate cardiotonic effect (slows down the rhythm and increases the strength of heart contractions), has moderate hypotensive properties.
Ethyl bromisovalerianate has a sedative and antispasmodic effect due to irritation, mainly of the oral and nasopharynx receptors, a decrease in reflex excitability in the central nervous system and an increase in inhibition in the neurons of the cortex and subcortical structures of the brain, as well as a decrease in the activity of central vasomotor spasms and direct places on smooth muscles. The nature of the action is similar to valerian preparations.
Motherwort herb has a pronounced sedative effect, reduces the frequency and increases the strength of the heartbeat, exhibits antihypertensive properties.
Peppermint oil has a vasodilating reflex, antispasmodic, mild choleretic, antiseptic effect. The mechanism of action is associated with the ability to irritate the cold receptors of the oral mucosa and reflexively expand the vessels of the heart and brain. Eliminates the phenomena of flatulence due to irritation of the receptors of the mucous membrane of the gastrointestinal tract (GIT), increasing intestinal motility.
Pharmacokinetics:
Pharmacokinetics of ethyl bromisovalerianate, motherwort herb, and peppermint components are not available.
Indications
As a symptomatic (sedative and vasodilator) agent for functional disorders of the cardiovascular system, neurosis-like conditions accompanied by increased irritability, in violation of falling asleep, tachycardia, a state of excitement with pronounced vegetative manifestations as an antispasmodic.
Contraindications
– Hypersensitivity to the components of the
preparation – severe impaired renal and / or liver function
– pregnancy
– lactation (breastfeeding)
– children under 18 years of age (efficacy and safety not established)
ore – lactase deficiency, glucose-galactose malabsorption.
If you have one of the listed diseases / conditions, be sure to consult your doctor before taking the drug.
Precautions:
Impaired renal and / or liver function.
Use during pregnancy and lactation
Safety of the drug Corvalol Fito, tablets during pregnancy have not been established, use of the drug during pregnancy is contraindicated.
There is no data on the penetration of the components of the drug into breast milk, so if you need to use the drug during lactation, you should decide whether to stop breastfeeding.
Special instructions
Experience with the use of the drug in children under 18 years of age, during pregnancy and during breastfeeding is absent.
Long-term use of the drug in high doses is not recommended, in connection with a possible toxic effect during the accumulation of bromine in the body.
Do not drink alcohol while using the drug.
Impact on the ability to drive transp. Wed and fur .:
Due to the possibility of dizziness, decreased attention span and other side effects associated with taking the drug, during the treatment period, patients are advised to refrain from driving vehicles and engaging in other potentially dangerous activities that require increased concentration of attention, speed of psychomotor and motor reactions.
Composition
Per tablet:
Active ingredients: motherwort herb extract (motherwort extract dry) – 14.00 mg or 28.00 mg, ethyl bromisovalerianate (ethyl ester of alpha-bromosovalerianic acid) – 8.20 mg or 16.40 mg, mint peppermint leaf oil (peppermint oil) – 0, 58 mg or 1.16 mg.
Excipients: lactose (lactose monohydrate) – 79.21 mg or 158.42 mg, betadex (beta-cyclodextrin) – 55.55 mg or 111.10 mg, potato starch – 35.56 mg or 71.12 mg, magnesium aluminometasilicate (Neusilin UFL 2) – 4.00 mg or 8.00 mg, talc – 2.00 mg or 4.00 mg, magnesium stearate – 0.90 mg or 1.80 mg.
Dosage and administration
For oral administration, before meals, with water.
For tablets, 0.58 mg + 14.00 mg + 8.20 mg: for adults, 2 tablets 2 times a day.
For tablets, 1.16 mg + 28.00 mg + 16.40 mg: for adults, 1 tablet 2 times a day.
With tachycardia, a single dose may be increased to 3 tablets. The maximum daily dose is 6 tablets.
The course of treatment is 4 weeks (28 days). The duration of admission can be increased on the recommendation of a doctor.
Side effects of
On the part of the immune system: allergic reactions
On the part of the central nervous system: drowsiness, weakness, dizziness, decreased ability to concentrate
On the part of the gastrointestinal tract: dyspepsia.
These phenomena occur when the dose of the drug is reduced or the drug is discontinued.
With prolonged use of high doses of the drug, the development of drug dependence is possible, as well as the accumulation of bromine in the body and the development of bromism, the manifestations of which are: depressed mood, apathy, rhinitis, conjunctivitis, hemorrhagic diathesis, impaired coordination of movements, drug dependence.
If any of the side effects listed in the instructions get worse, or if you notice any other side effects not listed in the instructions, notify your doctor.
Drug Interactions
With the simultaneous use of the drug Corvalol Fito, tablets with drugs that inhibit the activity of the central nervous system (sedatives, hypnotics, antipsychotics, tranquilizers), mutual effects may intensify.
Enhances the action of antispasmodic, analgesic agents.
Alcohol enhances the effect of the drug and its toxicity.
Overdose
Overdose is possible with frequent and prolonged use of the drug. If the recommended doses are exceeded, dose-dependent side effects may increase.
Symptoms: weakness, drowsiness, dizziness. With prolonged use, chronic bromine intoxication may occur (see section Side effects).
Treatment: symptomatic.
Storage conditions
At a temperature not exceeding 25 ° C.
Keep out of the reach and sight of children.
Expiration
2 years.
Do not use after the expiry date.
active substance
peppermint leaf oil, Leonurus herb extract, etylbromisovalerianate
conditions granted through pharmacies
without prescription
The dosage form of
tablet
