Description
Latin name
Sermion
Release form
film-coated tablets.
Packing
30 pcs
Pharmacological action
Pharmacodynamics
A drug that improves cerebral and peripheral blood circulation, with alpha-adrenergic blocking, as well as activating metabolism.
Reduces vascular resistance, increases arterial blood flow and the consumption of oxygen and glucose by brain tissues. Lowers pulmonary vascular resistance. Reduces platelet aggregation and improves hemorheological parameters.
Increases blood flow in the vessels of the upper and lower extremities, especially in cases of impaired blood flow due to functional arteriopathy. Clinical trials have shown Sermion’s high efficiency in cases of cerebrovascular accident and arterial blood flow insufficiency in the vessels of the upper and lower extremities.
Taking Sermion in therapeutic doses, as a rule, does not affect blood pressure. In patients with arterial hypertension, the drug can cause a gradual decrease in blood pressure.
Pharmacokinetics
Studies of the pharmacokinetics of Sermion have not been conducted.
Indications
Acute or chronic vascular or metabolic cerebral insufficiency: atherosclerosis thrombosis or cerebrovascular embolism transient cerebral ischemic attacks.
Acute or chronic peripheral vascular insufficiency: obliterating vascular disease of the extremities Raynaud’s syndrome other syndromes characterized by impaired peripheral circulation.
Headache.
Contraindications
Acute bleeding
acute myocardial infarction
orthostatic hypotension
hypersensitivity to nicergoline.
Use during pregnancy and lactation
During pregnancy, the drug is prescribed only for strict indications. In experimental studies, no teratogenic effect of nicergoline was revealed.
Composition
1 coated tablet contains:
Active substances: nicergoline – 5 mg.
Dosage and administration
Inside the drug is prescribed 5-10 mg 3 times / day with the same intervals between doses for a long period of time. To improve absorption, the drug should be taken between meals.
In some cases, it is advisable to start treatment with parenteral administration of the drug (Sermion por.liof.d / in. 4 mg fl. 4 ml [with r-lem] pack. 4 Pfizer), followed by oral administration during maintenance therapy.
Side effects
From the cardiovascular system: rarely – a feeling of heat and flushing of the face.
From the side of the central nervous system: rarely – drowsiness, insomnia.
From the digestive system: rarely – mild gastric disorders.
Drug Interaction
When used concurrently, Sermion may potentiate the effects of antihypertensive drugs.
Overdose
No case of overdose is currently described.
Storage conditions
Store at a temperature not exceeding 30 ° C.
Keep out of the reach of children.
Expiration
3 years.
Dosage form
Dosage form
tablets
