Description
Pharmacological action
Nifuroxazide – is a derivative of nitrofuran, has an antimicrobial effect. Highly active against Campylobacter jejuni, Escherichia coli, Salmonella spp., Shigella spp Clostridium perfringens, Vibrio cholerae, pathogenic Vibrions and Vibrio parahaemolytique, Staphylococcus spp. Weakly sensitive to nifuroxazide: Citrobacter spp, Enterobacter cloacae, Proteus indologenes.
Nifuroxazide Resistant: Klebsiella spp, Proteus mirabilis, Providencia spp., Pseudomonas spp. Presumably blocks the activity of dehydrogenases and inhibits the respiratory chain, the tricarboxylic acid cycle and a number of other biochemical processes in the microbial cell. Does not upset the balance of intestinal microflora.
In acute bacterial diarrhea, restores intestinal eubiosis. When infected with enterotropic viruses, it prevents the development of bacterial superinfection.
Pharmacokinetics
After oral administration, nifuroxazide is practically not absorbed from the gastrointestinal tract and has no systemic effect. 99% of the dose taken remains in the intestine and exerts its antimicrobial effect. Nifuroxazide is excreted by the intestines: 20% unchanged, and the remaining amount of nifuroxazide is chemically altered.
Indications
Acute bacterial diarrhea, proceeding without deterioration in general condition, fever, intoxication.
Contraindications
hypersensitivity to nifuroxazide, nitrofuran derivatives or any excipients of the
preparation children under 3 years of age (for this dosage form)
pregnancy
sucrose / isomaltase deficiency, fructose intolerance, glucose-galactose malabsorption.
Special instructions
In the treatment of diarrhea concomitantly with nifuroxazide therapy, rehydration therapy is necessary.
In the case of bacterial diarrhea with signs of systemic damage (general condition worsening, fever, symptoms of intoxication or infection), you should consult your doctor about the use of antimicrobial agents with a systemic effect.
The daily dose of 800 mg contains 0.023 XE.
Alcohol is not allowed during therapy with Eluphor.
If you experience symptoms of an allergic reaction (including shortness of breath, rash, itching), you should stop taking the drug and consult a doctor.
Effect on the ability to drive vehicles and mechanisms
The drug does not affect the ability to drive vehicles and mechanisms.
Dosage and Administration
Inside. The capsule should be swallowed whole with a little water.
Adults: 1 capsule of 200 mg 4 times a day (interval between doses 6 hours).
For children from 6 to 18 years: 1 capsule of 200 mg 3-4 times a day (the interval between doses is 6-8 hours).
For children from 3 to 6 years: 1 capsule of 200 mg 3 times a day (the interval between doses is 8 hours).
Duration of treatment 5-7 days, but not more than 7 days.
If no improvement occurs within the first 3 days of taking, then consult a doctor.
Use the drug only according to the method of use and at the doses indicated in the instructions. If necessary, please consult your doctor before using the medicine.
Side effects
Allergic reactions (skin rash, urticaria, Quincke’s edema, anaphylactic shock). If any of the side effects indicated in the instructions are aggravated, or if you notice any other side effects not listed in the instructions, inform your doctor.
Storage conditions
At a temperature not exceeding 25 ° C.
Keep out of the reach of children.
Shelf life
3 years. Do not use the drug after the expiration date.
Conditions of sale from
pharmacies Without prescription
