Description
Release form
Capsules.
Packaging
16 pcs.
Pharmacological action
Enterofuril ® is a broad-spectrum antimicrobial agent that does not have a systemic effect and is used to treat diarrhea of an infectious etiology. Enterofuril ® contains the active substance nifuroxazide, a drug of the 5-nitrofuran group of derivatives.
The drug has a bactericidal and bacteriostatic effect against most pathogens of acute intestinal infections. The antimicrobial effect of nifuroxazide is dose-dependent: for example, low and medium doses of the drug have a bacteriostatic effect against pathogenic microflora, and high ones have a bactericidal effect.
The bacteriostatic mechanism of action of the drug is associated with inhibition of the activity of the dehydrogenase enzyme, which leads to disruption of the normal course of the synthesis of vital compounds in the cell of a microorganism.
So, due to the influence of nifuroxazide on the cell of the microorganism, there is a violation of the respiratory chain, inhibition of the tricarboxylic acid cycle. In addition, Enterofuril ® inhibits the synthesis of proteins in the cell of the microorganism and inhibits other biochemical processes in the bacterial cell. Thus, the cell of the microorganism loses its ability to reproduce.
Indications
Diarrhea of bacterial origin.
Contraindications
Children under 3 years.
Hypersensitivity to nitrofuran derivatives or other components of the drug fructose intolerance, glucose-galactose malabsorption syndrome, or sucrose and isomaltase deficiency.
Special instructions
When treating diarrhea concomitantly with nifuroxazide therapy, rehydration therapy (oral or intravenous) must be carried out in accordance with the patient’s condition and the intensity of diarrhea.
The use of alcohol during nifuroxazide therapy is prohibited.
Before prescribing a suspension in infants, it is necessary to exclude their congenital deficiency of enzymes that break down sucrose.
Influence on the ability to drive vehicles and work with mechanisms.
The drug does not affect psychomotor activity and the ability to drive vehicles and work with mechanisms.
Composition
1 capsule contains:
Active ingredient:
nifuroxazide 200 mg,
Excipients:
sucrose – 71 mg
corn starch – 68 mg
MCC – 9 mg magnesium srdlp.
Shell:
gelatin
titanium dioxide
dye iron oxide yellow
Dosage and Administration
Inside. Nifuroxazide therapy should not last more than 7 days.
For adults and children over 7 years of age, the drug is prescribed 1 capsule (200 mg) 4 times a day, the daily dose is 800 mg.
For children 3 7 years of age, the drug is prescribed 1 capsule (200 mg) 3 times a day, the daily dose is 600 mg.
Side effects
Allergic reactions (rash, urticaria, Quincke’s edema, anaphylactic shock), nausea, vomiting.
Drug interaction
Not described.
Overdose
The drug is not absorbed from the gastrointestinal tract and does not enter the systemic circulation.
Overdose symptoms are not known. In case of overdose, gastric lavage and symptomatic treatment are recommended.
Storage Conditions
At 15 to 30 ° C.
Shelf life
3 years.
Active ingredient
Nifuroxazide
Terms and conditions
without prescription
dosage form
capsules
Possible product names
ENTEROFURIL 0.2 N16 CAPSA
Enterofuril 200mg Caps. X16
Enterofuril 200mg No. 16
Enterofuril 200mg No. 16 caps
ENTEROFURIL 200MG. No. 16 CAPS.
Bosnalek, Bosnia and Herzegovina
