Description
Pharmacological action of
Ivermek-spray has a pronounced acaricidal effect on the preimaginal and imaginal phases of sarcoptoid (Sarcoptes spp.decodisodes, apes, apodisores, apes, apodisores, apodisores, apodisores, apodisores, apodisores, apes. Demodex canis) ticks, parasitic in dogs, cats, fur-bearing animals and rodents, as well as knemidocoptotic ticks (Knemidocoptes spp.), parasitic in birds. The mechanism of action of ivermectin, which is part of the drug, is its effect on the value of the current of chlorine ions through the membranes of nerve and muscle cells of the parasite. The main targets are glutamate-sensitive chlorine channels, as well as gamma-aminobutyric acid receptors. A change in the current of chlorine ions disrupts the conduction of pulses, which leads to paralysis and death of parasites. Auxiliary components of the drug – panthenol and lidocaine have a wound healing and local anesthetic effect with a pronounced antipruritic effect, chlorhexidine bigluconate exhibits antibacterial and anti-inflammatory effects. After external use of the drug ivermectin, practically not absorbed into the systemic circulation, it mainly accumulates in the epidermis, hair follicles and sebaceous glands of the animal’s body, exerting an acaricidal effect for 5 to 7 days. Ivermek spray in terms of the impact on the body of warm-blooded animals belongs to low-hazard substances, in the recommended doses it does not have a skin-irritating and resorptive toxic effect. In case of contact with eyes, ivermek spray causes slight irritation. The drug is toxic to fish and bees.
Indications
Assign to dogs, cats, fur-bearing animals and decorative rodents for the treatment of sarcoptosis, otodectosis, notoedrosis, psoroptosis and demodecosis. Decorative bird – for the treatment of knemidocoptosis.
Contraindications
Hypersensitivity to the components of the drug. Animals under the age of 12 weeks, pregnant and lactating females, patients with infectious diseases, convalescent and exhausted animals cannot be treated with ivermek-spray.
Special instructions
During the procedure, you are not allowed to drink, smoke or eat. Processing of animals should be carried out with rubber gloves and a respirator (gauze bandage). After its completion, you need to wash your hands and face with warm water and soap, rinse your mouth with water. Do not allow animals to lick the preparation until the coat has completely dried out after treatment. Do not bathe and keep the animal in small children within 48 hours after treatment. If the drug enters the mucous membranes of the eyes and mouth, they must be thoroughly washed with a stream of water. It is forbidden to use containers from under the preparation for domestic purposes, it is thrown into garbage containers.
Composition
An acaricide in 1 ml contains 2.5 mg of ivermectin as an active ingredient, and 20 mg of lidocaine hydrochloride, 10 mg of panthenol and 0.5 mg of chlorhexidine bigluconate as auxiliary ingredients.
Dosage and administration
The animals are treated outdoors or in a well-ventilated area with open windows (windows), previously removing cages with decorative birds from the premises and covering aquariums with fish. To prevent drug licking, the animal is dressed with a muzzle, a neck collar or the jaw is fixed with a loop from the braid, which is removed after the skin-hair cover is completely dry. Ivermek spray is applied to the affected areas of the animal’s body, previously cleaned of scabs and crusts, before they are visually coated with the drug, but not more than 0.2 ml per 1 kg of the animal’s weight. The affected areas in the area of the eyes and nose are worked out with fingertips in a rubber glove moistened with the preparation, rubbing gently into the skin. When processing the bottle with the preparation is held upright and, pressing the spray head of the bottle, direct the aerosol torch to the affected areas from a distance of 10 – 20 cm with a capture of 1 – 2 cm of border healthy skin. When dogs, cats and fur-bearing animals with demodicosis, dogs and fur-bearing animals with sarcoptosis and cats are affected by knothedrosis, the treatment is carried out 2-4 times with an interval of 3-5 days before the clinical recovery of the animal, which is confirmed by two negative results of acarological studies. Animals with extensive lesion sites are treated in two divided doses with an interval of one day, applying the drug to the affected area, first one and then the other half of the body. With otodectosis (scabies) of carnivores and psoroptosis of decorative rodents, the drug is applied to the inner surface of the auricle and the skin of the external auditory canal, previously cleaned of scabs and crusts, depending on the weight of the animal and the size of the auricle in a dose of 0.5 – 1.0 ml corresponds to 4 to 9 presses on the spray head of the bottle. Processing is carried out twice with an interval of 3 to 5 days. If necessary, repeat the treatment. The drug must be administered in both ears, even in cases of otodectosis only one auricle. In advanced cases of the disease complicated by otitis, antibacterial and anti-inflammatory drugs are prescribed. Treatment of patients with knemidocoptosis of decorative birds is carried out 2 to 4 times with an interval of 3 to 5 days before the clinical recovery of the bird, which is confirmed by two negative results of acarological studies.
Side effects of
With proper use and dosage, side effects are generally not observed. With increased individual sensitivity of the animal to the components of the drug and the occurrence of complications (excessive salivation, lacrimation, muscle tremors, vomiting), the treatment with an acaricidal agent is stopped and the drug is washed off with water and a detergent.
dosage form
gel for external use
