Description
Packaging
30 sachets in 5 g
Pharmacological action of
Pharmacodynamics of
Hepa-Merz is involved in the ornithine Krebs urea cycle (urea biosynthesis from ammonia). Promotes the production of insulin and STH. Improves detoxification function of the liver, lowers elevated plasma ammonia levels. Improves protein metabolism in diseases requiring parenteral nutrition.
Pharmacokinetics
Dissociates into ornithine and aspartate, which are absorbed in the small intestine by active transport through the intestinal epithelium. It is excreted in the urine through a urea cycle.
Indications
Acute and chronic liver disease accompanied by hyperammonemia. Hepatic encephalopathy (latent and severe). Steatoses and steatohepatitis (of various origins).
Contraindications
Severe renal failure (serum creatinine> 3 mg / 1 dl)
Lactation (breastfeeding)
Hypersensitivity to the drug.
Use during pregnancy and lactation
During pregnancy, the use of Hepa-Merz is possible only under strict medical supervision. At the time of treatment, breast-feeding should be stopped
Special instructions
If you experience nausea or vomiting, reduce the rate of administration of the drug.
Influence on the ability to drive vehicles and control mechanisms
With hepatic encephalopathy, care must be taken when driving vehicles and engaging in other potentially dangerous activities, requiring increased concentration of attention and speed of psychomotor reactions.
Composition of
5g granules contain: Active ingredient:
L-ornithine-L-aspartate 3g
Excipients:
anhydrous citric acid 0.55 g, lemon flavor 0.02 g, orange flavor 0.2 g, sodium saccharin ( saccharin sodium) 0.0045 g, sodium cyclomat 0.0405 g, dye sunny sunset yellow 0.0005 g, polyvinylpyrrolidone (povidone) 0.05 g, fructose (levulose) 1.1345 g
Dosage and administration
Inside, after eating, 1 sachet of granulate, previously dissolved in 200 ml of liquid, 2-3 times a day.
Side effects
Rarely – skin reactions, in some cases – nausea, vomiting.
Overdose
Symptoms: increased severity of side effects.
Storage conditions
The product should be stored out of the reach of children at a temperature not exceeding 25 ° C.
Term hodnosty
5 years
Active ingredient
Ornithine
Terms leave through pharmacies
without prescription
oral dosage solution
oral dosage solution
