Description
Description
Afrin Moisturizing is a modern cold treatment in the form of a spray with a patented formula, due to which it is fixed on the nasal mucosa, acting in the epicenter of congestion from the 1st minute
Afrin Moisturizer does not flow from the nose and does not drain into the throat, helping to relieve congestion from the first minute and facilitates nasal breathing.
– Eliminates nasal congestion
– Facilitates nasal breathing
– Promotes hydration of the nasal mucosa
Afrin Moisturizing is indicated for symptomatic therapy: – Rhinitis (runny nose)
– Allergic rhinitis
– Sinusitis : – Eliminates the symptoms of runny nose and allergic rhinitis, helps moisturize dry and irritated nasal mucosa
– Does not reduce the effectiveness of the natural protection of the nose (1)
– Able to act be from 1 minute
– is able to maintain its effect until 12 hours
1. Oxymetazoline in a concentration of 0.05% has no effect on the activity of ciliated epithelium. Zhang L et al. Effect of oxymetazoline on healthy human nasal ciliary beat frequency measured with high-speed digital microscopy and mucociliary transport time. Ann Otol Rhinol Laryngol Feb 2008 117 (2): 12733.
Packing
Bottle of 15 ml
Pharmacological action
Alpha-adrenergic agonist for topical use.
Narrows the arterioles of the nasal mucosa, reduces swelling, hyperemia, and exudation of the mucosa.
Indications
symptomatic treatment of rhinitis (rhinitis) of allergic and / or infectious and inflammatory etiology4
sinusitis
eustachyitis
hay fever.
Contraindications
atrophic rhinitis
simultaneous use of MAO inhibitors (including the period of 14 days after their withdrawal)
children under 6 years of age.
hypersensitivity to the components of the drug
hypersensitivity to sympathomimetic drugs.
Precautions: coronary artery disease, arrhythmias, chronic heart failure, severe atherosclerosis, arterial hypertension, hyperthyroidism, diabetes mellitus, chronic renal failure, angle-closure glaucoma, prostatic hyperplasia with clinical symptoms, pregnancy, lactation.
Use during pregnancy and lactation
The safety of the drug in pregnant women and during lactation has not been established, therefore, the drug should be prescribed during pregnancy and during breastfeeding only on the recommendation of a doctor if the expected benefit of using the drug for the mother outweighs the potential risk for the fetus or baby.
Composition
1 ml contains:
Active ingredient:
oxymethazoline hydrochloride 0.5 mg
Excipients:
disodium edetate dihydrate – 300 μg,
sodium hydrogen phosphate – 975 μg sodium sulfide 5.5 gdrd srd 32 – 30 mg,
benzalkonium chloride solution 17% – 1.471 mg,
macrogol 1450 – 50 mg,
benzyl alcohol – 2.5 mg,
microcrystalline cellulose and sodium carmellose (Avicel RC-591) – 30 mg,
lemon flavor – 1.5 mg,
purified water – qs up to 1 ml.
Dosage and administration of
Intranasal.
Shake the bottle vigorously before each use.
Before using the nasal spray for the first time, you must calibrate it by pressing the spray head several times.
Adults and children over 6 years of age – 2-3 injections in each nasal passage with an interval of 10-12 hours. In adults, the frequency of use can be increased up to 3 times a day in adults.
It is not recommended to exceed the specified dose.
Side effects
Local reactions: transient dryness and burning of the nasal mucosa, dry mouth and throat, sneezing.
With prolonged use – tachyphylaxis, reactive hyperemia and atrophy of the nasal mucosa. Benzalkonium chloride, which is part of the drug, can cause local skin reactions.
Systemic reactions: increased blood pressure, increased anxiety, nausea, dizziness, headache, insomnia, palpitations, sleep disturbances.
Drug Interaction
The drug slows the absorption of locally anesthetized drugs and prolongs their duration.
Co-administration with other vasoconstrictor drugs increases the risk of side effects.
With the use of MAOI inhibitors (including a 14-day period after their withdrawal), maprolin and tricyclic antidepressants increase blood pressure.
overdose
Symptoms: nausea, vomiting, cyanosis, fever, tachycardia, arrhythmia, increase in blood pressure, shortness of breath, psychiatric disorders, CNS depression (drowsiness, shortness of breath, drowsiness, decrease in breath) and coma).
Treatment: symptomatic with accidental ingestion – gastric lavage, activated charcoal. Vasopressor medicines are contraindicated.
Storage conditions
At 2 30 ° C.
term life
5 Chron
Deystvuyuschee substances
oxymetazoline
pharmacy terms and conditions without a prescription
nasal spray dosage form
dosage form
nasal spray
Contract Pharmaceuticals Limited, Germany
