Description
Latin name
Rinzasip with Vitamin C
Release form
Rinzasip with vitamin C Lemon: powder from light yellow to yellow in color with white and yellow blotches.
Packaging
5 g – sachets (5) – packs of cardboard.
Pharmacological action
Rinzasip is a combination drug used for colds for symptomatic therapy.
Paracetamol – an analgesic-antipyretic, reduces the pain syndrome observed with colds – sore throat, headache, muscle and joint pain, reduces high body temperature.
Phenylephrine is a sympathomimetic, has a vasoconstrictive effect on peripheral vessels, reduces edema and hyperemia of the mucous membrane of the upper respiratory tract and sinuses.
Pheniramine – a blocker of histamine H1 receptors, has an anti-allergic effect: eliminates itching (including the eye, nose), swelling and hyperemia of the mucous membranes of the nasal cavity, nasopharynx and sinuses, reduces the phenomenon of exudation.
Caffeine has a stimulating effect on the central nervous system, which leads to a decrease in fatigue and drowsiness and to increase mental and physical performance.
Ascorbic acid (vitamin C) replenishes the increased need for vitamin C for colds and flu and increases the body’s resistance.
Indications
Symptomatic treatment of colds, flu, SARS (fever, pain, rhinorrhea).
Contraindications
hypersensitivity
simultaneous administration of drugs containing substances that are part of the drug
simultaneous administration of tricyclic antidepressants, MAO inhibitors, beta-adrenergic blockers
, intolerance, intolerance, intolerance, intolerance
children’s age (up to 15 years).
Precautions: severe atherosclerosis of the coronary arteries, arterial hypertension, thyrotoxicosis, pheochromocytoma, diabetes mellitus, bronchial asthma, chronic obstructive pulmonary disease, glucose-6-phosphate dehydrogenase deficiency, blood diseases, congenital hyperbilirubinemia (Gilbert, Dubin-Johnson and Rotor syndromes), liver and / or renal failure, angle-closure glaucoma, prostatic hyperplasia.
In the absence of a therapeutic effect (hyperthermia for more than 3 days and pain for more than 5 days), you should consult a doctor.
The drug contains sucrose, which must be considered for patients suffering from diabetes mellitus, as well as for patients on a low-calorie diet. A single dose of the drug contains from 2915 to 3136.0 mg of sucrose, which corresponds to 0.24 0.26 XE.
Use during pregnancy and lactation
The drug is contraindicated in pregnancy and lactation.
Ingredients
1 sachet (5 g) contains
Active ingredients:
paracetamol 750 mg,
ascorbic acid 200 mg,
caffeine 30 mg,
phenyramine maleate hydrochloric acid,
phenylephrine hydrochloric acid, hydrochloride – 200 mg,
sodium saccharin – 40 mg,
sodium citrate – 500 mg,
sucrose – 3136 mg,
dye – quinoline yellow (E104) – 1 mg,
lemon flavor – 83 mg.
Dosage and administration
Adults and children over 15 years of age are prescribed 1 sachet of Rinzasip 3-4 times a day with intervals between doses of at least 4-6 hours. The maximum daily dose is 4 sachets. The course of treatment should not exceed 5 days.
Rinzasip is taken 1-2 hours after a meal with plenty of fluids.
The contents of 1 sachet are dissolved in 1 cup of hot water (mix until completely dissolved). You can add sugar or honey.
The contents of 1 sachet are dissolved in 1 cup of hot water (mix until completely dissolved). You can add sugar or honey.
Side effects of
From the side of the central nervous system: dizziness, impaired falling asleep, increased irritability, mydriasis, increased intraocular pressure, paresis of accommodation.
From the cardiovascular system: increased blood pressure, tachycardia.
From the digestive system: nausea, epigastric pain, dry mouth, hepatotoxic effect.
From the hemopoietic system: anemia, thrombocytopenia, agranulocytosis, hemolytic anemia, aplastic anemia, methemoglobinemia, pancytopenia.
From the urinary system: urinary retention, nephrotoxic effect (papillary necrosis).
Allergic reactions: skin rash, itching, urticaria, angioedema.
Other: bronchial obstructive syndrome.
Drug Interaction
When used together, Rinsasip enhances the effects of MAO inhibitors, sedatives, and ethanol.
When used together with Rinsasip, antidepressants, antiparkinsonian agents, antipsychotic drugs, phenothiazine derivatives increase the risk of urinary retention, dry mouth, constipation.
When used together with ACS, they increase the risk of developing glaucoma.
Paracetamol reduces the effectiveness of diuretics used at the same time.
Tricyclic antidepressants increase the adrenomimetic effect of phenylephrine, prescription with halothane increases the risk of ventricular arrhythmia.
When used together, Rinsasip reduces the antihypertensive effect of guanethidine, which in turn enhances the alpha-adrenostimulating effect of phenylephrine.
Concomitant use of Rinsasip with barbiturates, diphenin, carbamazepine, rifampicin and other inducers of microsomal liver enzymes increases the risk of hepatotoxic action of paracetamol.
Overdose
10-15 g of paracetamol.
Symptoms: pallor of the skin, anorexia, nausea, vomiting, increased activity of hepatic transaminases, hepatonecrosis, liver failure (increase in prothrombin time).
Treatment: gastric lavage, inward – activated charcoal carrying out symptomatic therapy, methionine administration in 8-9 h after overdose and N-acetylcysteine in 12 h.
Storage conditions
The drug should be stored in a dry place inaccessible to children at a temperature not exceeding 25 ° C.
The Expiration of
is 3 years.
Deystvuyuschee substances
Paracetamol, ascorbic acid, caffeine, Fenyramyn, phenylephrine
Unique Pharmaceutical, India
