Description
release coating coated tablets
packaging 4 pcs
Pharmacological action
Combined preparation, has analgesic, antipyretic and anti-inflammatory effects.
Drotaverine – has a myotropic antispasmodic effect due to the inhibition of phosphodiesterase IV, acts on smooth muscles in the gastrointestinal tract, biliary tract, genitourinary and vascular systems.
Pheniramine is a H1-histamine receptor blocker. It has an antispasmodic and mild sedative effect, reduces the effects of exudation, and also enhances the analgesic effect of paracetamol and naproxen.
Paracetamol is a non-narcotic analgesic, has an antipyretic and analgesic effect, due to the blockade of cyclooxygenase in the central nervous system and the impact on the centers of pain and thermoregulation.
Naproxen is a non-steroidal anti-inflammatory drug that has anti-inflammatory, analgesic and antipyretic effects associated with non-selective suppression of the activity of cyclooxygenase that regulates prostaglandin synthesis.
Caffeine – causes the expansion of blood vessels of skeletal muscles, heart, kidneys, increases mental and physical performance, helps to eliminate fatigue and drowsiness, increases the permeability of histohematological barriers and increases the bioavailability of non-narcotic analgesics, thereby enhancing the therapeutic effect. It has a tonic effect on the vessels of the brain.
Indications
mild to moderate pain syndrome of various origins (including joint pain, muscle pain, radiculitis, algodismenorrhea, neuralgia, headache, migraine, toothache)
fever, colds and other diseases accompanied by pain and inflammation.
Contraindications
severe liver failure
severe renal failure
gastric and duodenal ulcer in the acute phase
bronchial asthma
bronchospasm
anemia leukopenia
conditions accompanied by respiratory depression
traumatic brain injury
severe arterial hypertension
acute myocardial infarction
arrhythmias
intoxication
glaucoma glucose-6-deficient child-specific drug.
With caution, the drug should be used for mild and moderate arterial hypertension, gastric and / or duodenal ulcer in remission, as well as in elderly patients.
Use during pregnancy and lactation
The use of the drug during pregnancy and during lactation (breastfeeding) is contraindicated.
Composition
1 tablet contains:
paracetamol 325 mg,
naproxen 100 mg,
caffeine 50 mg,
drotaverine hydrochloride – 40 mg,
pheniramine maleate – 10 mg
excipients: microcrystalline
microcrystalline cellulose, potato starch
, croscarmellose sodium
, hyprolose
(hydroxypropyl cellulose (EF cluccel), citric acid monohydrate
, srldkl srld, yellow st
indigo carmine (E 132).
Dosage and administration of
Pentalgin is taken orally 1 tablet 1-3 times a day.
The maximum daily dose is 4 tablets.
Duration of treatment is not more than 3 days as an antipyretic and not more than 5 days as an anesthetic.
Continuation of treatment with the drug is possible only after consulting a doctor.
Side effects
Allergic reactions: skin rash, itching, urticaria, angioedema
Hematopoietic organs: thrombocytopenia, leukopenia, agranulocytosis, anemia, nervousness anxiety, nervousness, nervousness, nervousness, nervousness, nervousness, nervousness, nervous system, sleep disturbances, dizziness, decreased concentration
From the cardiovascular system: palpitations, arrhythmias, increased blood pressure
From the digestive system: erosive-ulcerative lesions of the gastrointestinal tract, nausea, vomiting, epigastric discomfort, abdominal pain, constipation, abnormal liver function
From the urinary system: renal dysfunction
From the senses: hearing loss, tinnitus, increased intraocular pressure in patients with angle-closure glaucoma
Other: dermatitis, tachypnea (rapid breathing).
Overdose
Symptoms: nausea, vomiting, gastralgia, drowsiness, tachycardia, heart rhythm disorders, delirium, weakness, respiratory depression.
Treatment: induction of vomiting, gastric lavage through a probe, appointment of adsorbents (activated charcoal), symptomatic therapy aimed at maintaining vital functions.
Storage conditions
Store in a dry, dark place at a temperature not exceeding 25 ° C.
Expiration
1 year.
Active ingredient
Paracetamol, Naproxen, Caffeine, Caffeine taveryn, Fenyramyn
Pharmacy terms
OTC
Dosage form
dosage form
tablets
Pharmstandard-Leksredstva, Russia
