Description
Release form
film-coated tablets
Packing
20 pcs.
Pharmacological action
Pharmacodynamics. Antispasmodic with selective action on the gastrointestinal tract. Inhibits the entry of calcium into the cells of the smooth muscles of the intestine. Animal studies have shown that pinaveria bromide reduces the effects of stimulation of sensitive neurons. It does not have an anticholinergic effect. It does not affect the cardiovascular system.
Pharmacokinetics. After oral administration of pinaveria, bromide is rapidly absorbed and reaches a maximum plasma concentration after one hour. Pinaveria bromide has a high ability to bind to plasma proteins (95-96%). The drug is actively metabolized in the liver. The half-life is 1.5 hours. The absolute bioavailability is very low (less than 1%). It is excreted mainly with feces.
Indications
spasms of the smooth muscles of the abdominal cavity: dyskinesia of the colon, biliary dyskinesia
preparation for X-ray of the gastrointestinal tract using barium.
Contraindications
hypersensitivity,
paralytic bowel obstruction,
atony of the intestine,
toxic megacolon,
severe ulcerative colitis.
Use during pregnancy and lactation
During pregnancy and lactation (breastfeeding) Ditetel is prescribed only in cases where the intended benefits to the mother outweigh the potential risk to the fetus or baby.
Special instructions
Dietitel is prescribed for children only in cases where the intended benefit outweighs the potential risk.
Composition
1 film-coated tablet contains:
Active ingredient: pinaveria bromide – 100 mg.
Excipients: colloidal silicon dioxide – 2.00 mg, microcrystalline cellulose – 158.70 mg, talc – 6.00 mg, magnesium stearate – 3.00 mg, pregelatinized starch – 34.00 mg, lactose monohydrate – 36.30 mg
Film coating: basic butyl methacrylate – 16.352 mg, sodium lauryl sulfate – 1.636 mg, talc – 12.946 mg, stearic acid – 2.384 mg, dry sepispers 3203 – 0.682 mg (hypromellose (E 464) – 55.0-65.0%, microcrystalline cellulose (E 460) – 5.015.0%, titanium dioxide (E 171) – 20.0-30.0%, sunset sunset dye yellow (aluminum varnish) (E 110) – 3.0%).
Dosage and administration of
Dietel is prescribed for adults 1 tablet 2 times a day (morning and evening).
If necessary (in exceptional cases), the dose can be increased to 3 tablets per day
Side effects
From the digestive system: rarely – dyspepsia, constipation, nausea.
Other: rarely – allergic reactions.
Overdose
Symptoms: an overdose can lead to gastrointestinal upsets, such as flatulence and diarrhea.
Treatment: specific antidote unknown symptomatic treatment recommended.
Storage conditions
Keep out of the reach and sight of children at temperatures not exceeding 25 ° C.
Expiration
5 years.
active substance
pinaverium bromide
Terms leave through pharmacies
In retseptu
The dosage form of
tablet
Indications
Indications
From biliary dyskinesia, From gastrointestinal spasms, To prepare for bonds and abdominal x-ray
