Description
Latin name
Vizomitin
Packing
5 ml – dropper bottle (1) – packs of cardboard.
Pharmacological action of
Plastoquinonyl decyl triphenylphosphomy bromide (PDTF) is a derivative of plastoquinone, which is linked via a linker chain (CJ) to the triphenylphosphine residue. PDTF in low (nanomolar) concentrations exhibits high antioxidant activity. It also has a stimulating effect on the process of tear production, epithelization, helps to increase the stability of the tear film.
Pharmacokinetics
No pharmacokinetic studies in humans have been conducted. In preclinical animal studies, the distribution of PDTF in organs and tissues occurred within 48 hours after iv and intragastric administration. It was found that PDTF is present in the highest concentrations in the tissues of the kidney, liver and heart within 1 h after administration. PDTF undergoes relatively fast enzymatic cleavage and covalent binding to proteins.
Indications
Dry eye syndrome.
Contraindications
hypersensitivity to the components of the drug Visomitin
age under 18 years.
Use during pregnancy and lactation
Adequate controlled studies in pregnant and lactating women have not been conducted. It is not recommended to prescribe the drug during pregnancy. If necessary, the appointment during lactation for the treatment period, breastfeeding should be discontinued.
Composition
Eye drops transparent or slightly opalescent, colorless or slightly colored.
1 ml
plastoquinonyl decyl triphenylphosphonium bromide 0. 155 mcg
Excipients: benzalkonium chloride 0.1 mg, hypromellose 2 mg, sodium chloride 9 mg, sodium dihydrogen phosphate 0.81 mg, sodium hydrogen phosphate dodecahydrate 116.35 mg, sodium hydroxide solution 1 M to pH 6.3-7.3, water d / and up to 1 ml.
Dosage and Administration
Topically (in the conjunctival sac). 1-2 drops of the drug 3 times a day. The duration of treatment is determined by the doctor depending on the severity of the symptoms.
Side effects
Allergic reactions.
Storage Conditions
In a dark place at 2-8 ° C.
Shelf life
1 year. Use the opened bottle for 1 month.
Terms and conditions
prescription
dosage form
eye drops
Possible Product Names
Visarzine Ku-Tab Oral Dispersible tablets 50 mg 8 pcsfrd8 sprff8 mg 8 pcsfrd8 mg 8 pcsfrd 4 mg 4 pcs Visomitin eye drops 5 ml
Mitotech, Russia
