Description
Latin name
Enterosgelum
Release form
Pasta for oral administration
Packaging
225 g
Pharmacological action
Clinical and pharmacological group
Enterosorbent.
Pharmacological action
Enterosgel has a porous structure of an organosilicon matrix (molecular sponge) of a hydrophobic nature, which is characterized by a sorption effect with respect to only molecular toxic toxic metabolites (m.m. from 70 to 1000).
Pharmacodynamics
Enterosgel has pronounced sorption and detoxification properties. In the lumen of the gastrointestinal tract, the drug binds and removes endogenous and exogenous toxic substances of various nature from the body, including bacteria and bacterial toxins, antigens, food allergens, drugs and poisons, salts of heavy metals, alcohol.
The drug also absorbs some metabolic products of the body, including excess bilirubin, urea, cholesterol and lipid complexes, as well as metabolites responsible for the development of endogenous toxicosis. Enterosgel does not reduce the absorption of vitamins and minerals, helps to restore impaired intestinal microflora and does not affect its motor function.
Pharmacokinetics
The drug is not absorbed in the gastrointestinal tract, excreted unchanged within 12 hours.
Indications
Enterosgel is used in adults and children as a detoxifying agent:
acute and chronic intoxication of various origins
acute poisoning with potent and toxic substances, including, drugs and alcohol, alkaloids, salts of heavy metals
acute intestinal infections of any genesis as part of complex therapy (toxicoinfection, salmonellosis, dysentery, diarrheal syndrome of non-infectious origin, dysbacteriosis)
purulent-septic diseases accompanied by severe complexion intoxication,
food and drug allergy
hyperbilirubinemia (viral hepatitis) and hyperazotemia (chronic renal failure)
to prevent tics of chronic intoxication to workers in hazardous industries (professional intoxication with polytropic chemical agents, xenobiotics, incorporated radionuclides, lead, mercury, arsenic compounds, petroleum products, organic solvents, nitrogen oxides, carbon oxides, fluorides, salts of heavy metals).
Contraindications
Contraindication for use of Enterosgel is:
hypersensitivity to the drug
gastrointestinal bleeding
intestinal obstruction.
Use during pregnancy and lactation
Enterosgel is not contraindicated during pregnancy and lactation (breastfeeding).
Composition of
100 g of oral paste contains:
Active ingredients:
polymethylsiloxane polyhydrate (non-linear polycondensation product 1,1,3,3-tetrahydroxy-1,3-dimethyldisiloxane polyhydrate) 70 g.
Excipients:
purified water – 30 g.
Dosage and administration of
Dosage and administration of
Inside, 1-2 hours before eating or taking other drugs with water.
It is recommended to take with a glass of water or before taking a dose in half a glass of water.
Dosing regimen for different age groups
Dosage for adults – 1 packet or 22.5 g (1.5 tbsp) 3 times a day. The daily dose is 67, 5 g (3 packets)
Dosage for children aged 5 to 14 years – 15 g (1 tablespoon) 3 times a day. The daily dose is 45 g (2 packets)
Dosage for children under the age of 5 years is 7.5 g (0.5 tbsp) 3 times a day. The daily dose is 22.5 g (1 packet).
Dosage for infants – it is recommended to stir 2.5 g (0.5 tsp) of the drug in a triple volume of breast milk or water and give before each feeding (6 times a day).
Dosing regimen depending on the symptoms
For the prevention of chronic intoxication – one packet or 1.5 tbsp. tablespoons (22.5 g) 2 times a day for 7-10 days, monthly.
Use for acute diarrhea:
Dosage for adults and children from 5 years: initial dose – 2 packets or 45 g (3 tablespoons) for adults and 1 packet or 22.5 g (1.5 tablespoons) for children , in the future, take 1 packet or 22.5 g (1.5 tbsp) after each bowel movement in case of loose stool.
Dosage for children under 5 years: initial dose – 1 tablespoon (15 g), then take 1.5 teaspoons (7.5 g) after each bowel movement in case of loose stool.
After diarrhea stops, take the drug for 5 days at the usual dosage.
In severe intoxications during the first three days, the dose of the drug can be increased by 2 times.
The duration of treatment for acute poisoning is 3-5 days, for chronic intoxications and allergic conditions – 2-3 weeks.
Repeated course – on the recommendation of a doctor.
Side effects
From the digestive system: possibly – nausea, constipation.
Other: in severe renal or hepatic insufficiency, a feeling of aversion to the drug may occur.
Drug Interaction
When co-administered with Enterosgel, the absorption of other drugs may be reduced.
Overdose
No cases of overdose have been detected with Enterosgel.
Storage conditions
At a temperature not lower than 4 ° C (do not freeze). Protect from drying after opening the package
Expiration
3 years.
Deystvuyuschee substances
Polymetylsyloksana polyhydrat
Pharmacy leave conditions
Over-the-counter
dosage form
dosage form
gel ingestion