Description
Latin name
CORTEXIN
Release form
Lyophil atm for solution for intramuscular administration.
Packaging
10 vials
Pharmacological action
A drug that improves brain metabolism. Cortexin is a lyophilisate obtained by acetic acid extraction from the cerebral cortex of cattle or pigs, containing low molecular weight active neuropeptides, the molecular weight of which does not exceed 10,000 daltons, sufficient for penetration through the BBB.
Cortexin has a tissue-specific multifunctional effect on the brain, which is manifested in metabolic regulation, neuroprotection, functional neuromodulation, neurotrophic activity.
Cortexin increases the efficiency of energy metabolism of brain cells, improves intracellular protein synthesis.
Cortexin regulates the processes of lipid peroxidation in brain cells, reduces the formation of free radicals, and blocks the processes of free radical oxidation. The drug eliminates the imbalance of inhibitory and excitatory amino acids, has a moderate GABA-ergic effect.
The drug has a positive effect on cognitive impairment, improves concentration, short-term memory, learning ability, accelerates the restoration of brain functions after stress, regulates the level of serotonin and dopamine.
Stimulates the process of mental activity without exerting an excessive activating effect, restores the bioelectric activity of the brain.
Cortexin stimulates reparative processes in the brain.
Indications
– cerebrovascular accident
– encephalopathy of various genesis
– acute and chronic encephalitis and encephalomyelitis
– vegetative-vascular dystonia
– sirpklrrdkrplodenum
psychomotor and speech development in children
– asthenia
– impaired memory, thinking, decreased learning ability.
Contraindications
Individual intolerance to the drug.
Special instructions
It is recommended that you consult a specialist before use.
Dosage and administration
The drug is administered intramuscularly.
The contents of the bottle before injection are dissolved in 1-2 ml of a 0.5% solution of procaine (novocaine), water for injection or a 0.9% sodium chloride solution, directing the needle to the wall of the bottle to prevent foaming, and administered once daily: for adults, at a dose 10 mg for 10 days for children with a body weight of up to 20 kg at a dose of 0.5 mg / kg, with a body weight of more than 20 kg – at a dose of 10 mg for 10 days.
If necessary, repeat the course after 3 6 months.
In hemispheric ischemic stroke in the acute and early recovery periods, adults at a dose of 10 mg 2 times a day (morning and afternoon) for 10 days, with a repeated course in 10 days.
Side effects
No side effects reported.
Possible individual hypersensitivity to the components of the drug.
Drug interaction
Drug drug interaction not described.
Storage Conditions
The product should be stored in a dry, dark place at 2 ° to 20 ° C.
Expiration
2 years.
Conditions prescription from pharmacies
Prescription
lekarstvennaja form
Solution for
