Polyvytamyn parenteral Introduction – Zernevit vials 10 pcs

$68.00

Description

Product form

lyophilisates for solution for intravenous administration

Packing

10 fl.

Pharmacological action of

Zernevit is a balanced mixture of water-soluble and fat-soluble vitamins, providing a complete supply of vitamins for parenteral nutrition

Indications

Supplement to parenteral nutrition for adults and children over 11 years of age.

Contraindications

hypersensitivity to the components of the drug, especially vitamin B1

children under 11 years of age

concomitant use of levodopa preparations

Special instructions

With bolus intravenous administration, rare cases of a moderate increase in ALT (CHPT) in patients with active enterocolitis have been observed after the end of the use of Cernevit, elevated levels of hepatic transaminases quickly return to normal values. It is recommended to control the levels of œliver transaminases in patients of this group.

Due to the presence of glycocholic acid as an auxiliary ingredient, with repeated and prolonged injections of the drug in patients with jaundice or severe cholestasis (changes in laboratory functional tests of the liver), liver function should be carefully monitored.

Deficiency of one or more vitamins should be corrected with special medications.

Zernovit does not contain vitamin K, which can be taken separately, if necessary.

Composition

Each vial (5 ml) contains:

Active ingredients:

Retinol (Vitamin A) in the form of 35 retinol palate ME

Colecalciferol (Vitamin D3) 220 ME,

Alpha-Tocopherol (Vitamin E) 11.2 ME, corresponds to the amount of DL Alpha-Tocopherol 10.2 mg,

Ascorbic Acid (Vitamin C) 125 mg,

Thiamine (Vitamin B1) 3.51 mg, in the form cocarboxylase tetrahydrate 5.8 mg,

Riboflavin (vitamin B2) 4.14 mg, in the form of riboflavin sodium phosphate dihydrate 5.67 mg,

Pyridoxine (vitamin B6) 4.53 mg, in the form of pyridoxine hydrochloride 5.50 mg,

Cyanocobalamin 6 žÑ˜m, (

acid (vitamin B9) 414 mcg,

Pantothenic acid (vitamin B5) 17.25 mg, in the form of dexpanthenol 16.15 mg,

Biotin (Vitamin B8) 0.069 mg,

Nicotinamide (Vitamin PP) 46 mg,

Excipients: glycine, glycocholic acid, soy phosphatides, sodium hydroxide, hydrochloric acid.

Dosage and administration

iv, 747 mg / day (1 vial, 5 ml per day). The contents of the vial are diluted in 5 ml of water for injection, injected iv or diluted with 5% glucose solution or 0.9% sodium chloride solution and injected infusion. It is possible to add to nutrient mixtures containing carbohydrates, lipids, amino acids and electrolytes, provided that compatibility and stability were previously confirmed for each type of nutrient mixture used. Application can last the entire period of parenteral nutrition.

Side effects of

In rare cases, in some patients, an increase in ALT (SGPT) may occur with intravenous bolus administration.

Since the preparation contains vitamin B1, anaphylactic reactions may develop in patients with delayed-type allergies.

Please consult a doctor immediately if you have noticed any adverse reactions not listed above when using the drug.

Drug interaction

Due to the presence of pyridoxine (vitamin B6) in the preparation, the combined use with levodopa preparations is contraindicated.

Due to the presence of folic acid in the preparation, caution should be exercised when combined with antiepileptic drugs containing phenobarbital, phenytoin or primidone: clinical observation and, if possible, monitoring of blood plasma levels are necessary, correction of the dosage regimen of an antiepileptic drug during and after cessation of folic acid use.

Compatibility should be checked when preparing with other infusion solutions, especially if Zernevit is added to binary parenteral mixtures containing glucose, electrolytes and amino acid solutions or to mixtures containing glucose, electrolytes, amino acid solutions and lipids.

Please tell your doctor or pharmacist which medications you used previously, even if they were prescribed without a prescription.

Overdose

Symptoms: manifested by signs of an overdose of vitamin A. At a dose of vitamin A more than 150,000 IU, gastrointestinal upsets, headache, increased intracranial pressure, swelling of the optic nerve head, mental disturbances, agitation or convulsions, delayed desquamation of the epithelium, manifestations of chronic intoxication with vitamin A: increased intracranial pressure Sensitive or painful subcutaneous bulging on the fingers of the upper and lower extremities.

Treatment: stopping the drug, taking measures to reduce calcium intake and increase diuresis, adequate rehydration of the body.

Storage Conditions

Do not store above 25 ° C, in a dark place

Expiration

3 years.

Active ingredient

Multivitamin, parenteral administration

Terms leave through pharmacies

In retseptu

lekarstvennaja form

Solution for infusion

Baxter, United States