Description
Release form
Tablets
Pharmacological action of
Iodine drug for the prevention and treatment of thyroid diseases
Indications
prophylaxis of iodine deficiency diseases, incl. endemic goiter (especially in pregnant and lactating women)
prevention of relapse of goiter after surgical removal or after treatment of goiter with thyroid hormone preparations
treatment of diffuse euthyroid goiter in newborns, children, adolescents and adult young patients.
Contraindications
hyperthyroidism
subclinical hyperthyroidism when taking doses of iodine more than 150 mcg per day
herpetiform Dühring dermatitis
solitary toxic thyroid adenomas and functional thyroid gland autonomy (focal neoplastic therapy) glands)
hypersensitivity to iodine.
Potassium iodide should not be taken for hypothyroidism, unless the development of the latter is caused by severe iodine deficiency.
Prescribing should be avoided with radioactive iodine therapy if there is or is suspected of thyroid cancer.
Since the drug contains lactose monohydrate, it is not recommended for patients with rare hereditary diseases associated with galactose intolerance, lactase deficiency or glucose-galactose malabsorption.
Use during pregnancy and lactation
During pregnancy, use is only possible in recommended doses, as iodine crosses the placental barrier and can cause the development of hypothyroidism and goiter in the fetus.
Iodine is excreted in breast milk.
When used in the mother during lactation (breastfeeding) in doses of more than 1 mg / day, there is a risk of hypothyroidism in the infant.
Special instructions
Hyperkalemia may develop in patients with renal failure during therapy.
Composition
Active ingredient:
potassium iodide 262 mcg (corresponding to 200 mcg iodine).
Excipients:
magnesium hydroxycarbonate (basic magnesium carbonate) – 0.0175 g
lactose (milk sugar) – 0.059738 g microcrystalline
microcrystalline cellulose – 0.02 g
magnesium stearate – 0.001 g
silicon dioxide colloid) 0.0005 g
croscarmellose sodium – 0.001 g
Dosage and administration of
When determining the required dose of the drug, regional and individual characteristics of the intake of iodine with food must be taken into account. This is especially important when prescribing the drug to newborns and children under 4 years of age.
Prevention of iodine deficiency diseases:
Newborns and children: 50-100 mcg iodine per day (?? 1 tablet of the drug Potassium iodide 100 mcg)
Adolescents and adults: 100-200 mcg of iodine per day (1 tablet of Potassium iodide 100 mcg or 1 tablet of Potassium iodide 200 mcg)
During pregnancy and during breastfeeding: 100-200 mcg of iodine per day (1 tablet of Potassium iodide 100 mcg or 1 tablet of the drug Potassium iodide 200 mcg).
Prevention of relapse of goiter after surgical removal or after treatment of goiter with thyroid hormone preparations:
100-200 mcg iodine daily (1 tablet of Potassium iodide 100 mcg or 1 tablet of Potassium iodide 200 mcg).
Treatment of euthyroid goiter
Newborns and children: 100-200 micrograms of iodine per day (1 tablet of potassium iodide 100 micrograms or 1 tablet of potassium iodide 200 micrograms)
Adolescents and young adults: 200 mcg of iodine per day (2 tablets of Potassium iodide 100 mcg or 1 tablet of Potassium iodide 200 mcg).
The daily dose should be taken in one dose, after meals, with plenty of fluids. When prescribing the drug to newborns and children under 3 years of age, it is recommended to dissolve the tablet in a small amount (1 tablespoon) of boiled water at room temperature.
Prophylactic use of the drug is usually carried out for several months or years, and often? throughout life. For the treatment of goiter in newborns, in most cases, 2-4 weeks in children, adolescents and adults usually takes 6-12 months or more.
Duration of treatment is determined by the physician.
Side effects
Allergic reactions are rare: skin rash, Quincke edema.
Drug Interactions
With simultaneous high-dose therapy with iodine and potassium-sparing diuretics, hyperkalemia may develop, with lithium preparations, goiter and hypothyroidism may develop. Perchlorate and thiocyanate competitively inhibit the absorption of iodine by the thyroid gland, and TSH stimulates.
Antithyroid drugs weaken the effect (mutually).
Overdose of
When prescribing the drug at a dose of more than 150 mcg per day for patients who have foci with functional autonomy in the thyroid gland, iodine-induced hyperthyroidism may develop.
During therapy with high doses of iodine (more than 1,000 micrograms per day), in some cases, goiter and hypothyroidism may develop.
Chronic overdose can lead to the phenomenon of iodism : metallic taste in the mouth, swelling and inflammation of the mucous membranes (rhinitis, conjunctivitis, gastroenteritis, bronchitis), acne, dermatitis, swelling of the salivary glands, fever, irritability.
Treatment: in case of chronic overdose, it is recommended to discontinue use of the drug. With the development of iodine-induced hyperthyroidism, it is recommended to discontinue use of the drug and prescribe therapy with antithyroid drugs. In especially severe cases, intensive therapy, plasmapheresis or thyroidectomy is necessary.
With the development of hypothyroidism, it is recommended to stop using the drug and prescribe therapy with iodine-containing thyroid hormones.
Storage Conditions
In a dark place at a temperature not exceeding 25 ° C.
Keep out of the reach and sight of children.
Active ingredient
Potassium iodide
Pharmacy terms of sale
Over-the-counter
Form of Treatment
tablets
Upgrading PFC, Russia
