Description
Packing
10 ampoules of 1 ml.
Pharmacological action
Pyridoxine hydrochloride – Vitamin B6. Phosphorylated and in the form of pyridoxalphosphate is part of enzymes that catalyze decarboxylation and transamination. It plays an important role in the metabolism of tryptophan, glutamic acid, cysteine, methionine, as well as in the transport of amino acids through the cell membrane. It is necessary for the activation of phosphorylase, for the formation of neurotransmitters, gamma-aminobutyric acid, glycine, serotonin. Participates in the exchange of vitamin B12, folic acid, in the synthesis of porphyrins, in the exchange of unsaturated fatty acids. It is used to activate metabolic processes in myofibrils, especially with myocardial hypoxia. The daily requirement for adults is 2–2.5 mg, for children from 6 months to 1 year — 0.5 mg, 1–1.5 years — 0.9 mg, 1.5–2 years — 1 mg, 3– 4 years – 1.3 mg, 5-6 years old – 1.4 mg, 7-10 years old – 1.7 mg, 11-13 years old – 2 mg, for boys 14-17 years old – 2.2 mg, for girls 14-17 years old – 1.9 mg
Indications
B6-hypovitaminosis, toxicosis of pregnant women, sideroblastic anemia, leukopenia, central nervous system diseases (parkinsonism, small chorea, Little’s disease, radiculitis, neuritis, neuralgia, Meniere’s disease), sea and airborne disease, non-peborrheic, non-peborrheic, non-peborrheic, non-choleroborrheic, non-peborrheic and neuroboric diseases dermatitis, herpes zoster, neurodermatitis, psoriasis, exudative diathesis, the use of drugs of the isoniazid group.
Contraindications
Hypersensitivity. With caution: peptic ulcer of the stomach and duodenum.
Composition
1 ampoule (1 ml) contains: pyridoxine hydrochloride 50 mg, water for injection up to 1 ml.
Dosage and administration
Subcutaneously, intramuscularly and intravenously. Adults are usually prescribed 0.05-0.1 g per day in 1-2 doses, for children 0.02 g. The course of treatment for adults is 1 month, for children 2 weeks.
For the treatment of sideroblastic anemia – 0.1 g intramuscularly 2 times a week. It is advisable to take folic acid, cyanocobalamin, riboflavin at the same time.
With parkinsonism – 2 ml of a 5% solution per day intramuscularly. The course of treatment is 20-25 injections. After 2-3 months, the course is repeated.
In depressions of involutional age, 0.2 g per day is administered intramuscularly.
Side effects
Allergic reactions, increased acidity of gastric juice.
Drug interactions
Isoniazid, cycloserine, penicillamine reduce the effect. Pharmaceutically incompatible with vitamins B1 and B12. It weakens the antiparkinsonian activity of levodopa.
Storage conditions
In the dark place.
active substance
Pyridoxine
Prescription conditions
prescription from
pharmacies Prescription
lekarstvennaja form
Solution for
Yerevan HFF, Armenia
