Description
Release form
Cream for external use 0.2%.
Packaging
Tube 50 g.
Pharmacological action
Pharmacotherapeutic group
Dermatoprotective agent.
CodeATX [D 11 AX 12]
Pharmacological properties of
Pharmacodynamics
Activated zinc pyrithione has anti-inflammatory, antibacterial and antifungal activity. Antifungal activity is especially pronounced against Pityrosporum ovale and Pityrosporum orbiculare, which support inflammation and excessive desquamation during dandruff, seborrhea, psoriasis and other skin diseases. Zinc pyrithione reduces intracellular ATP levels, contributes to the depolarization of cell membranes and the death of fungi and bacteria.
Pharmacokinetics
For external use, activated pyrithione zinc is deposited in the epidermis and surface layers of the dermis. Systemic absorption occurs slowly. The drug is found in the blood in trace amounts.
Indications
Psoriasis, atopic dermatitis, eczema, neurodermatitis, dry skin, seborrheic dermatitis in adults and children from 1 year old.
Contraindications
Hypersensitivity to the components of the drug.
Use during pregnancy and lactation
During pregnancy and lactation, the drug should be prescribed only in cases where the expected benefits of therapy for the mother outweigh the potential risk to the fetus or infant.
No adverse effects were reported with the use of zinc pyrithione preparations by pregnant women and women during breastfeeding.
Special instructions
In case of contact with eyes, rinse with plenty of cold water.
Composition of
100 g of the preparation contain:
Active ingredient:
pyrithione zinc activated 200 mg
Excipients:
glyceryl mono- and distearate (Tegin M),
capryl caprylate (Tegosstroper ether, Tegospert Erod,) Tegosoft E20),
isopropyl palmitate (Tegosoft R),
methyl dextrose polyglyceryl distearate (Togo Car 450),
butylhydroxytoluene,
glycerol,
propyl parahydroxybenzoic acid (s) fatty acid and hydrochloride acid alcohol (tego alkano l 18),
ethanol,
flavoring agent (citronellol, phenylethanol, geraniol, terpineol, cinnamon alcohol),
cyclomethicone (Abil K 4),
water.
Dosage and Administration
Externally. After vigorous shaking, the cream is applied in a thin layer to the affected areas of the skin 2 times a day. The course of treatment for psoriasis is 1-1.5 months, with atopic dermatitis 3-4 weeks.
Method of administration and doses in pediatrics: method of administration and doses in children do not differ from the method of administration and doses in adults.
If necessary, a second course of treatment can be carried out 1-1.5 months after consulting a doctor.
Side effects
Allergic reactions.
In the first days of treatment, there may be a short-term burning sensation at the site of application of the drug, which, as a rule, does not require discontinuation of the drug.
Drug Interactions
No clinically significant interactions of Skin-cap with other drugs have been identified.
Storage conditions
At a temperature of +4 to +20 ° C, out of the reach of children.
Expiration
3 years.
active substance
Pyrithione zinc
lekarstvennaja form
cream
l.Bra.A.Bra. Raun Medical SA, Spain
