Description
Latin name
Remantadin
Release form
Tablets.
Packing
20 tablets.
Pharmacological action
Remantadine is an antiviral drug, a derivative of amantadine, or medantan, which is used as an antiparkinsonian drug and, at the same time, is a specific chemotherapeutic drug with antiviral activity. Remantadine is active against various strains of the influenza A virus (especially A2), and is active against tick-borne encephalitis viruses (Central European and Russian spring-summer), which belong to the Arbovirus family of the Flaviviridae family. The main mechanism of antiviral action is the inhibition of the early stage of specific reproduction after the virus enters the cell and before the initial transcription of RNA.
The pharmacological effectiveness of the drug is provided by inhibiting the reproduction of the virus in the initial stage of the infectious process.
Indications
– early treatment and prevention of influenza in adults and children over 7 years old
– prevention of influenza during epidemics in adults
– prevention of tick-borne encephalitis of viral etiology.
Contraindications
– acute liver disease
– acute and chronic kidney disease
– thyrotoxicosis
– pregnancy
– hypersensitivity to the drug.
Special instructions
When using Remantadine, an exacerbation of chronic concomitant diseases is possible. In elderly patients with arterial hypertension, the risk of developing hemorrhagic stroke is increased.
With influenza caused by virus B, rimantadine has an antitoxic effect. Prophylactic is effective in contact with patients with the spread of infection in closed groups and at high risk of the disease during an influenza epidemic. Perhaps the emergence of drug-resistant viruses.
Composition
1 tablet contains 50 mg of rimantadine.
Side effects
From the side of the central nervous system: decreased ability to concentrate, insomnia, dizziness, headache, nervousness, excessive fatigue.
From the digestive system: dry oral mucosa, anorexia, nausea, gastralgia, vomiting.
Drug Interactions
Paracetamol and ASA reduce Cmax of rimantadine by 11 and 10%, respectively.
Cimetidine reduces rimantadine clearance by 18%.
Storage Conditions
Keep out of the reach and sight of children.
Expiration
5 years.
Eff active substance
rimantadine
Terms leave through pharmacies
without prescription
lekarstvennaja form
tablets
Indications
Influenza, Prevention of influenza, Tick-borne encephalitis, SARS
Possible product names
REMANTADIN 0.05 N20 TABLE / OLYNFARM /
Remantadine 0.05 Tab. X20
Remantadine 0.05 Tab. X20 /! Until 10.09 /
Remantadine 0.05 Tab. X20 /! Until 11.09 /
Remantadine tab 0.05 N20
