Description
Release form
solution for infusion
Pharmacological action
Sodium chloride – detoxification.
Pharmacodynamics
It has a detoxifying and rehydrating effect. Replenishes sodium deficiency in various pathological conditions. 0.9% sodium chloride solution is isotonic to human plasma and therefore rapidly excreted from the vascular bed, only temporarily increasing bcc (effectiveness with blood loss and shock is insufficient).
Pharmacokinetics
Sodium concentration – 142 mmol / L (plasma) and 145 mmol / L (interstitial fluid), chloride concentration – 101 mmol / L (interstitial fluid). It is excreted by the kidneys.
Indications
large loss of extracellular fluid or insufficient intake (toxic dyspepsia, cholera, diarrhea, “indomitable” vomiting, extensive burns with severe exudation, etc. a)
hypochloremia and hyponatremia with dehydration
intestinal obstruction
intoxication
washing the wounds, eyes, nasal mucosa, dissolving and diluting drugs and moisturizing dressings.
Contraindications
hypernatremia
acidosis
hyperchloremia
hypokalemia
extracellular hyperhydration
intracellular dehydration
circulatory disorders, threatening cerebral and pulmonary edema
cerebral edema
pulmonary edema
acute left ventricular failure
concomitant administration of large doses of corticosteroids.
Precautions:
renal failure
heart failure
oligo- and anuria.
Composition
Active ingredients:
sodium chloride 9 g
Excipients:
water for injection – up to 1 l
Dosage and administration
Intravenous drip, externally.
Before administration, the solution is heated to 36 38 ° C. The dose is determined depending on the body’s loss of fluid, Na + and Cl , and averages 1000 ml per day. With large losses of fluid and severe intoxication, up to 3000 ml per day can be administered. The speed of administration – 540 ml per hour, if necessary – the speed of administration is increased.
Children with dehydration, expressed in a decrease in blood pressure (without determining laboratory parameters) are administered 20-30 ml / kg. In the future, the dosage regimen is adjusted depending on laboratory parameters. With long-term administration of large doses of isotonic sodium chloride solution, it is necessary to control the content of electrolytes in plasma and urine.
Isotonic sodium chloride solution is used to wash wounds, eyes, nasal mucosa, moisturize dressings.
Side effects
Acidosis, hyperhydration, hypokalemia.
Storage conditions
In a dry, dark place at a temperature of no higher than 25 ° C.
Expiration date
1 year
Active ingredient
Sodium chloride
lekarstvennaja form
Solution for infusion
Appointment
Adult by appointment, Nursing moms, Children by doctor’s appointment, Pregnant doctor by appointment
Indications
for preparing medicaments solutions
