Description
active substance
yoversol
Pharmacological action
Guttasil – laxative.
Indications
Constipation or cases requiring relief of bowel movements (hemorrhoids, proctitis, anal fissures, preparation for surgical interventions, instrumental and radiological examinations).
Contraindications
hypersensitivity to sodium picosulfate and other components of the drug
intestinal obstruction
acute inflammatory bowel disease and acute diseases of the abdominal cavity (including acute appendicitis, nonspecific ulcerative colitis, peritonitis and acute pain) vomiting, which may indicate acute inflammatory diseases, severe dehydration
pregnancy (I trimester)
lactation.
Use during pregnancy and lactation
Caution:
elderly patients, hypokalemia, high blood magnesium, patients with asthenia, II III trimesters of pregnancy.
Special instructions
Like other laxatives, guttasil should not be taken daily for a long time. If necessary, daily use of laxatives should determine the cause of constipation. Long-term use of laxatives can lead to electrolyte imbalance and hypokalemia, as well as become addictive and constipation due to the effect of rebound.
Guttasil is effective in eliminating constipation in cancer patients receiving high doses of opioids.
The drug contains sorbitol, therefore, patients with rare hereditary fructose intolerance are not recommended to take it.
Influence on the ability to drive vehicles and work with mechanisms. In therapeutic doses, the drug does not affect the ability to drive vehicles and work with other mechanisms.
Composition
1 tab. sodium picosulfate 7.5 mg
Excipients: sorbitol 460 mg, sodium methyl paraoxybenzoate 2.0 mg, hydrochloric acid 1 M to pH 6.0-7.0, water d / and up to 1 ml.
Dosage and administration
Inside, at night (so that the stool is the next morning).
Side effects
Skin side: skin rash, urticaria, itching.
From the side of the water-electrolyte balance: loss of potassium, sodium and other electrolytes, dehydration may develop.
From the digestive system: dyspeptic symptoms, vomiting, nausea, cramping and abdominal pain, diarrhea, flatulence, pain in the stomach and anus, increased intestinal motility, which pass with a decrease in the dose of the drug.
From the side of the immune system: allergic reactions, angioedema.
From the side of the central nervous system: headache, fatigue, drowsiness, cramps.
Drug Interactions
Electrolyte imbalance can lead to decreased cardiac glycoside tolerance. Diuretics or corticosteroids can increase the severity of hypokalemia caused by the use of guttasil in high doses. Simultaneous treatment with antibiotics can reduce the laxative effect of the drug.
overdose
Symptoms: high doses of Guttasil can cause fluid stools, abdominal cramps and clinically significant abnormalities in water-electrolyte balance (hypokalemia, loss of other electrolytes and fluid), mucosal colonic mucosa. Prolonged overdose leads to the development of chronic diarrhea and abdominal pain, hypokalemia, secondary hyperaldosteronism, kidney damage and the development of nephrolithiasis, metabolic alkalosis, hypokalemia, and muscle weakness as a result of hypokalemia.
Treatment:
gastric lavage, appointment of enterosorbents (activated charcoal), symptomatic treatment (correction of water-electrolyte balance, appointment of antispasmodics).
Storage conditions
In a dark place, at a temperature of 15-25 ° C.
Shelf life
3 years
dosage form
tablets
Possible product names
Guttasil 7.5 mg oral tablets 30 pcs
Farmak, Ukraine
