Description
Release form
Drops for oral administration
Packing
Bottle of 10 ml.
Pharmacological action
Laksigal – laxative. The active form of the drug, formed by hydrolysis under the influence of intestinal microorganisms, directly excites the nerve structures of the intestinal wall, as a result of which the intestinal contents are accelerated, the absorption of electrolytes and water decreases.
Action occurs 10-12 hours after administration.
Pharmacokinetics
After oral administration, it is not absorbed from the gastrointestinal tract and does not undergo hepatic-intestinal circulation.
Indications
atonic constipation
stool regulation (hemorrhoids, proctitis, anus fissures)
preparation for surgery, instrumental and radiological examinations.
Contraindications
intestinal obstruction
strangulated hernia
acute inflammatory diseases of the abdominal cavity
peritonitis
abdominal pain (gastrointestinal tract)
dr I trimester)
hypersensitivity.
Caution: lactation.
Composition
1 ml contains:
Active ingredient: sodium picosulfate monohydrate (in terms of 100% substance) 7.5 mg
Excipients: sorbitol liquid 70% uncrystallized – 680 mg ethyl parahydroxybenzoate sodium – 0.66 mg chloride – to the required amount of water up to – 1 ml.
Dosage and administration
Inside, at bedtime, diluted in a small amount of water.
Adults and children over 10 years old – 12-24 drops (5-10 mg).
For children from 4 to 10 years old – 6-12 drops (2.5-5 mg).
Depending on the effect, the dose is increased or decreased in subsequent doses.
Side effects
Possible: diarrhea, abdominal pain, dehydration, disturbances in water-electrolyte balance, weakness, cramps, decreased blood pressure.
Drug Interactions
May increase sensitivity to cardiac glycosides.
corticosteroids, diuretics increase the risk of electrolyte disturbances.
Broad-spectrum antibiotics reduce the laxative effect.
Overdose
Symptoms: chronic overdose may develop ischemia of the mucous membrane of the colon, secondary hyperaldosteronism, urolithiasis, damage to the renal tubules.
Treatment: gastric lavage, correction of disturbances in water-electrolyte balance, antispasmodics.
Storage Conditions
At 15-25 ° C (do not freeze).
Term hodnosty
3 years
Prescription conditions from
pharmacies Without prescription
lekarstvennaja form
Drops for pryema inside
Teva Pharmaceutical Enterprise Co., Ltd., Israel
