Description
Latin name
Streptocidum
release form
Powder for external use.
Packing
2 g bag.
Pharmacological action
Streptocide is a broad-spectrum antibacterial agent. Sulfanilamide (streptocide) is one of the first representatives of chemotherapeutic agents of the sulfonamide group. It has a bacteriostatic effect. The mechanism of action is due to competitive antagonism with PABA and competitive inhibition of the enzyme dihydropteroate synthetase. This leads to a violation of the synthesis of dihydrofolium, and then tetrahydrofolate acid and as a result – to a violation of the synthesis of nucleic acids.
Sulfanilamide is active against gram-positive and gram-negative cocci, Escherichia coli, Shigella spp., Vibrio cholerae, Haemophilus influenzae, Clostridium spp., Bacillus anthracis, Corynebacterium diphtheriae, Yersinia pcespplam, Ch. .
Indications
Infected wounds of various etiologies, burns of I and II degrees, superficial pyoderma, boils, carbuncles, acne vulgaris, impetigo and other purulent-inflammatory skin diseases.
Contraindications
Hypersensitivity,
anemia,
renal / liver failure,
congenital glucose-6-phosphate dehydrogenase deficiency,
azotemia,
porphyria,
pregnancy,
lactation.
Use during pregnancy and lactation
Contraindicated in the I and II trimesters of pregnancy and during lactation.
Composition
Active ingredient: sulfonamide.
Dosage and administration
For external use, apply to affected areas of the skin and mucous membranes. Dressings are performed in 1-2 days.
Side effects
From the digestive system: nausea, vomiting, diarrhea.
From the hemopoietic system: rarely – eosinophilia, thrombocytopenia, leukopenia, hypoprothrombinemia, agranulocytosis.
From the side of the central nervous system and peripheral nervous system: in isolated cases – visual impairment, headache, dizziness, peripheral neuropathy, ataxia.
Other: skin allergic reactions rarely – nephrotoxic reactions (most likely in patients with impaired renal function) In rare cases – hypothyroidism.
Drug Interactions
Myelotoxic drugs enhance the hematotoxicity of the drug.
Overdose
Symptoms: nausea, vomiting, intestinal colic, dizziness, headache, drowsiness, depression, unconsciousness, visual impairment, fever, hematuria, crystalluria with prolonged overdose, overdose,
Treatment: copious drink by accidentally taking ointment and powder inside – gastric lavage.
Storage Conditions
In a dark place at a temperature not exceeding 25 ° C.
active substance
sulfanilamide
Terms leave through pharmacies
without prescription
lekarstvennaja form
powder for external use
Prescription
For children prescribed by the doctor, For adults
Indications
Indications
From boils, From skin infections, Purulent wounds, Burns, From bedsores, From pyoderma
Lumi, Russia
