Description
Latin name
Kornam
Release form
Tablets.
Packaging
In a blister pack of 10 tablets. In training 3 blisters.
Indications
– Benign prostatic hyperplasia (symptomatic treatment).
– Arterial hypertension.
Contraindications
– Children.
– Hypersensitivity to the drug.
Precautions should be given in patients with angina pectoris, coronary heart disease, liver or kidney failure, cerebrovascular accident, type 1 diabetes mellitus.
Use during pregnancy and lactation
Corn can be used during pregnancy and during breastfeeding if the potential benefit to the mother outweighs the potential risk to the fetus or infant.
Composition
IN 1 tab
Excipients: lactose monohydrate, microcrystalline cellulose, corn starch, talc, dye yellow (E104), anhydrous colloidal silicon dioxide, magnesium stearate.
Dosage and administration of
In benign prostatic hyperplasia, the initial dose is 1 mg 1 time / day. before bedtime. Gradually, the dose is increased to 2-10 mg / day. to achieve the optimal effect. The therapeutic effect is usually observed 2 weeks after the start of treatment. To achieve a lasting effect, the course of treatment should be 4-6 weeks.
In arterial hypertension, the drug is prescribed in an initial dose of 1 mg / day. before bedtime. Gradually increase the dose until a clinical effect is achieved. The maintenance dose is 1-10 mg 1 time / day. The maximum daily dose is 20 mg. In the case of a temporary discontinuation of the drug, treatment is resumed according to the same scheme.
Side effects
– In the treatment of benign prostatic hyperplasia
From the cardiovascular system: rarely – orthostatic hypotension.
From the side of the central nervous system: drowsiness, dizziness, asthenia.
Other: nasal congestion.
– In the treatment of arterial hypertension
From the cardiovascular system: orthostatic hypotension is the first dose effect (observed in 1% of patients, mainly receiving diuretics or beta-blockers), manifested by dizziness, tachycardia, fainting is rare – a feeling of palpitations, peripheral edema, nasal congestion.
From the side of the central nervous system: rarely – dizziness, asthenia, drowsiness, impaired clarity of visual perception.
From the hemopoietic system: a decrease (associated with hemodilution) of hematocrit, hemoglobin, leukopenia, hypoproteinemia, hypoalbuminemia.
Other: rarely – decreased potency, nausea.
Drug Interaction
When used with Kornam and beta blockers, diuretics, calcium channel blockers, ACE inhibitors, the antihypertensive effect may be enhanced. Particular caution is required with the simultaneous administration of terazosin and central antihypertensive drugs.
The absorption of terazosin is reduced by the simultaneous administration of adsorbents and antacids.
Adrenomimetics attenuate the effect of terazosin.
The simultaneous use of terazosin and NSAIDs may reduce the antihypertensive effect due to inhibition of prostaglandin synthesis and retention of fluid and sodium ions.
Overdose
Symptoms: severe BP, impaired movement coordination, fainting.
Treatment: It is necessary to lay down the patient by lowering the head end of the bed. If necessary, appoint hypertensive agents, in / in the introduction of fluid. Hemodialysis is not effective.
Storage conditions
At a temperature not exceeding 25 ° C.
Expiration
3 years.
Deystvuyuschee substances
terazosin
Pharmacy
Prescription
dosage form
dosage form
tablets
sandoz, switzerland
