Description
Latin name
Termicon
packaging
bottle 15 g
Pharmacological action
Thermicon – antifungal drug, allylamine. It has a wide range of antifungal effects.
Active against dermatophytes: Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton tonsurans, Trichophyton verrucosum, Trichophyton violaceum, Microsporum canis, Epidermophyton floccosum.
At low concentrations, it has a fungicidal effect on dermatophytes, molds (including Aspergillus, Cladosporium, Scopulariopsis brevicaulis) and some dimorphic fungi. On yeast fungi of the genus Candida (mainly Candida albicans) and their mycelial forms, depending on the species, the drug has a fungicidal or fungistatic effect.
Thermicon disrupts the early stage of biosynthesis of the main component of the cell membrane of the ergosterol fungus by inhibiting the squalene epoxidase enzyme. This leads to a deficiency of ergosterol and to intracellular accumulation of squalene, which causes the death of the fungal cell. The action of terbinafine is carried out by inhibiting the enzyme squalene epoxidase located on the cell membrane of the fungus.
Pharmacokinetics
When applied externally, the spray is absorbed less than 5% of the dose, so the systemic effect of the drug is minimal.
Indications
Prevention and treatment of fungal infections of the skin, including mycoses of the feet, inguinal epidermophytosis (tinea cruris), fungal lesions of smooth skin of the body (tinea corporis) caused by dermatophytes such as Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton tonsurans, Trichophyton verrucosum, Trichophyton violaceum, and Microsporum fungus canis inflorescis canisum (Malassezia furfur).
Use during pregnancy and lactation
Thermicon should be used according to strict indications and if the intended benefits to the mother outweigh the potential risk to the fetus.
In experimental studies of teratogenic properties of terbinafine have not been identified. To date, no malformations have been reported with Thermicon.
Terbinafine is excreted in breast milk. However, if the Thermicon spray is used by the nursing mother, a small amount of the active substance is absorbed through the skin, so an adverse effect on the baby is unlikely.
Composition
1 bottle (vial) contains:
Active ingredient:
terbinafine hydrochloride (terbinafine) – 0.15 g
Excipients:
ethanol (srldpolprpolprldpolrpolprpolprldpolrpolprldpolprp peeled.
Dosage and Administration
Externally.
Thermicon spray for adults can be used 1 or 2 times a day, depending on the indications.
Before using the product, thoroughly clean and dry the affected areas of the skin.
During use, the balloon (bottle) should be held upright.
To ensure uniform spraying of the contents, first make a few short presses on the spray nozzle.
The drug is applied to the affected areas of the skin and adjacent areas of healthy skin in an amount sufficient to moisturize them.
Duration of treatment and frequency of use of the drug:
dermatomycosis of the trunk, legs: 1 week, 1 time per day
dermatomycosis of the feet: 1 week, 1 time per day
versicolor versicolor: 1 week, 2 times per day
inguinal epidermophytosis, diaper rash, molds: 1 week, 1 time per day.
Dosing regimen Thermicon spray in the elderly does not differ from the above.
Experience in using Thermicon Spray in children under 12 years of age is limited, and therefore the use of the drug in children is not recommended.
Side effects
Local reactions: in the places where the cream is applied, redness, itching or burning sensation, allergic reactions are possible.
Overdose
No cases of overdose have been reported. If Termicon ® is accidentally taken orally, the same symptoms as overdosage of the pills can be expected: headache, nausea, epigastric pain, and dizziness.
Treatment: activated charcoal, if necessary – symptomatic supportive therapy.
Storage conditions
At a temperature not exceeding 30 ° C.
Do not freeze.
Keep out of the reach and sight of children.
Shelf life
2 years.
Active ingredient
Terbinafine
Terms and conditions
without prescription
dosage form
spray for external use
Possible product names
TERMIKON 1% 15.0 SPRAY
Thermicon 1% 15g spray
TERMIKON 1% 15G. SPRAY
TERMICON SPRAY 1% 15G
Thermicon spray 1% vial 15g
Pharmstandard-Leksredstva, Russia
