Description
Release form
Vizin. Eye drops.
Packaging
15 ml – plastic bottles with dropper 1).
Pharmacological action
alpha-adrenergic agonist. Tetrizoline stimulates the -Adrenoreceptors of the sympathetic nervous system, does not or has a weak effect on -Adrenoreceptors.
Has a vasoconstrictor effect and reduces tissue edema.
The drug begins 60 seconds after instillation and lasts 4-8 hours.
Pharmacokinetics
Tetrizoline is practically not absorbed when applied topically.
No detailed pharmacokinetic studies have been performed with eye drops.
Indications
Conjunctival edema and hyperemia caused by allergies or due to exposure to chemical and physical factors (smoke, dust, chlorinated water, light, cosmetics, contact lenses).
The drug is prescribed for adults and children over 2 years of age.
For children under 6 years of age, the drug is prescribed under the supervision of a physician.
Contraindications
endothelial-epithelial corneal dystrophy
angle-closure glaucoma
children under 2 years of age
hypersensitivity to the components of the drug.
Caution should be used in patients with severe cardiovascular diseases (e.g., coronary heart disease, arterial hypertension, arrhythmias, aneurysms), hyperthyroidism, diabetes mellitus, pheochromocytoma, and in patients receiving MAO inhibitors or other drugs that can increase blood pressure.
Use during pregnancy and lactation
Given the risk of developing systemic adverse reactions, the drug can be used during pregnancy and lactation (breastfeeding) only in cases where the intended benefit of the therapy for the mother outweighs the potential risk to the fetus or infant.
Special instructions
Before burying the drug, contact lenses must be removed and installed approximately 15 minutes after instillation.
It is advisable to use the drug only with mild eye irritation. The patient should be warned that if the condition does not improve within 48 hours or if irritation and hyperemia persist or increase, the drug should be discontinued and a doctor should be consulted.
The patient should be informed that if there is intense pain in the eyes, headache, loss of vision, the sudden appearance of floating spots in front of the eyes, redness of the eyes, pain when exposed to light, or when double vision occurs, consult a doctor immediately.
The drug should not be used if irritation or hyperemia is associated with serious diseases of the organ of vision, such as an infection, a foreign body, or chemical trauma to the cornea.
The patient should be informed that if the medicine has become unusable or has expired, then it should not be thrown into wastewater or into the street. It is necessary to put the medicine in a bag and put in a garbage container. These measures will help protect the environment.
Influence on the ability to drive vehicles and control mechanisms
In rare cases, after applying eye drops, pupil dilates and blurred vision occurs, which can affect the ability to drive a car or mechanisms.
Composition
1 ml – tetrizoline hydrochloride 500 mcg
Excipients:
boric acid,
sodium chloride,
disodium edetate,
benzalkonium chloride solution 17%,
sodium boron.
Dosage and administration
Instill 1-2 drops in the affected eye 2-3 times / day.
Continuous use of the drug for more than 4 days is not recommended.
When instilling, remove the cap from the dropper bottle and turn the bottle over.
Avoid touching the tip of the dropper to any surface.
After use, screw on the cap of the dropper bottle.
Side effects
From the side of the organ of vision: in rare cases, burning sensation, redness of the eye, pain and tingling in the eye, blurred vision, irritation of the conjunctiva, dilated pupil.
The patient should be warned that if any adverse reactions develop, consult a doctor immediately.
Overdose
When using the drug in accordance with the instructions, the risk of developing an overdose is minimal. However, if the drug enters the gastrointestinal tract, the following symptoms are possible: pupil expansion, nausea, cyanosis, fever, convulsions, tachycardia, arrhythmia, cardiac arrest, hypertension, pulmonary edema, respiratory dysfunction, central nervous system function, coma.
The risk of overdose symptoms associated with drug absorption is high in newborns and young children, especially when swallowing drops.
Treatment: if necessary, activated charcoal, gastric lavage, oxygen inhalation, antipyretic and anticonvulsants are prescribed. To reduce blood pressure, iv administration of 5 mg of phentolamine in physiological saline or oral administration of phentolamine in a dose of 100 mg is possible. For patients with low blood pressure, vasopressor agents are contraindicated. The specific antidote is unknown.
Storage conditions
The product should be stored out of the reach of children at a temperature not exceeding 30 ° C.
The Expiration of
is 3 years.
The contents of the open vial should be used for 4 weeks.
active substance
tetryzoline
Conditions of dispatch from
pharmacies Without prescription
Dosage form
eye drops
keatite Pharma Inc., Canada
