Description
Latin name
Trimedat forte
Release form
Round biconvex tablets coated with a white film coating with an extruded symbol in the form of two drop-shaped elements on one side. In a cross section, the core is white or almost white.
Pharmacological action of
Trimebutin, acting on the intestinal enkephalinergic system, is a regulator of its peristalsis. Acting on peripheral -, – and receptors, including those located directly on smooth muscle throughout the gastrointestinal tract (GIT), it regulates motility without affecting the central nervous system.
Thus, trimebutin restores the normal physiological activity of the intestinal muscles in various diseases of the gastrointestinal tract associated with impaired motor skills.
Normalizing visceral sensitivity, trimebutin provides an analgesic effect in abdominal pain.
Indications
Symptomatic treatment of pain, cramping and discomfort in the abdomen, bloating (flatulence), motor bowel disorders with changes in stool frequency (diarrhea or constipation), dyspepsia, heartburn, belching, nausea, and vomiting of organs associated with gastrointestinal function intestinal tract and biliary tract (non-erosive form of gastroesophageal reflux disease gallstone disease biliary tract dysfunction irritable bowel syndrome sphincter of Oddi dysfunction, postcholecystectomy cue syndrome).
Postoperative paralytic intestinal obstruction.
Contraindications
Hypersensitivity to the components that make up the drug.
Pregnancy.
Children under 12 years of age (for this dosage form).
Caution: The drug Trimedat ® forte should be used with caution during breastfeeding, since there is no data on its ability to pass into breast milk.
Use during pregnancy and lactation
In experimental studies, no data were found on teratogenicity and embryotoxicity of the drug. However, due to the lack of necessary clinical data, the use of the drug Trimedat ® forte during pregnancy is contraindicated.
It is not recommended to prescribe Trimedat ® forte during lactation, due to the lack of reliable clinical data confirming the safety of the drug during this period. If necessary, use the drug during lactation should stop breastfeeding.
Special instructions
To prevent recurrence of irritable bowel syndrome after a course of treatment during the period of remission, it is recommended to continue taking a dose of 300 mg per day for 12 weeks.
Impact on the ability to drive transp. Wed and fur .:
The drug does not have a sedative effect, does not affect the speed of the psychomotor reaction and can be used in persons of various professions, including those requiring increased attention and coordination of movements. However, given the possible side effects that may affect these abilities (dizziness and others), care should be taken when driving and engaging in other potentially dangerous activities.
Composition of
One tablet contains:
Active ingredient:
trimebutine maleate – 300 mg
Excipients:
microcrystalline cellulose,
povidone (K 25),
hypromellose srdlprd22 srdlprd, srdlprd, srdlprd partially hydrolyzed polyvinyl alcohol, macrogol-3350, titanium dioxide E 171, talc.
Dosage and Administration
Inside.
Adults and children over 12 years of age, 1 tablet 2 times a day (with a break of 12 hours).
The course of treatment for abdominal pain associated with functional diseases of the digestive tract and biliary tract is 28 days.
Side effects of the
From the digestive system: dry mouth, unpleasant taste, diarrhea, dyspepsia, nausea, constipation.
From the nervous system: drowsiness, fatigue, dizziness, headache, anxiety.
Allergic reactions: skin rash.
Other: menstrual irregularities, painful enlargement of the mammary glands, urinary retention.
Drug interaction
Drug interaction of the drug Trimedat ® forte is not described.
Overdose
No overdose of Trimedat ® Fort has been reported to date.
Treatment: cancellation of the drug, gastric lavage, appointment of activated charcoal, symptomatic therapy. There are no specific antidotes.
Storage Conditions
In original packaging at a temperature not exceeding 25 ° C.
Keep out of the reach and sight of children.
Shelf life
2 years.
Do not use after the expiration date printed on the package.
Deystvuyushtee substance
trimebutine
Terms and conditions
without prescription
dosage form
tablets
Possible Product Names
Trimedat Forte Tablets 300 mg 20 pcs.
