Description
Pharmacological action
Semi-synthetic bioflavonoid (rutin derivative) of the benzopyran class. Venotonic, antiprotective agent. Reduces the permeability and fragility of capillaries, strengthens the vascular wall, improves microcirculation, has a decongestant effect. Participates in redox processes, has antioxidant activity. It increases the density of the vascular wall, reduces the exudation of the liquid part of blood plasma and the diapedesis of blood cells in the tissue, reduces inflammation in the vascular wall, limiting the adhesion of platelets to its surface.
The use of troxerutin is possible both at the initial and late stages of treatment of chronic venous insufficiency, it is possible to use it as one of the components of complex treatment.
Troxerutin reduces swelling and a feeling of heaviness in the legs, reduces the intensity of pain and cramps, improves trophic tissue.
Troxerutin relieves symptoms associated with hemorrhoids (pain, exudation, itching, bleeding).
Due to its effect on the permeability and resistance of capillary walls, troxerutin slows the progression of diabetic retinopathy.
The effect of troxerutin on the rheological properties of blood helps prevent the development of retinal vascular microthrombosis.
Indications
– chronic venous insufficiency
– trophic disorders in chronic venous insufficiency (dermatitis, trophic ulcers)
– varicose veins
– superficial thrombophlebitis, periflebitis
– post-thrombotic hemorrhoid syndrome retinopathy.
Contraindications
– Hypersensitivity to troxerutin and other components of the drug
– peptic ulcer of the stomach and duodenum
– chronic gastritis (in the exacerbation phase)
– pregnancy (I trimester) sr application experience is limited).
Precautions:
In patients with chronic renal failure (prolonged use).
Special instructions
The experience with troxerutin in children under the age of 18 is insufficient.
In the treatment of superficial thrombophlebitis or deep vein thrombosis, the use of troxerutin does not exclude the need for prescribing anti-inflammatory and antithrombotic agents.
Impact on the ability to drive transp. Wed and fur .:
Taking troxerutin does not affect motor and mental reactions, does not interfere with driving and working with mechanisms.
Composition
1 capsule contains:
active ingredient: troxerutin 300 mg
excipients: macrogol 6000 12.00 mg, magnesium stearate 3.12 mg
capsule shell: body – titanium dioxide 2%, gelatin up to 100% cap – dye quinoline yellow 0.713%, iron dye oxide red 0.005%, titanium dioxide 2.000%, gelatin up to 100%.
Dosage and Administration
Inside. Capsules should be swallowed whole, with food, with plenty of fluids.
The drug troxerutin is used as directed by a physician.
Usually, 1 capsule is prescribed orally 3 times a day as maintenance therapy – 1 capsule 2 times a day.
The course of treatment averages 3-4 weeks, the need for a longer treatment is determined individually.
Side effects
Troxerutin is very well tolerated, in rare cases mild adverse reactions occur.
Disorders of the immune system: hypersensitivity reactions.
Disorders of the nervous system: headache.
Disorders of the gastrointestinal tract: irritation of the gastrointestinal mucosa, nausea.
Disorders of the skin and subcutaneous tissues: skin rashes, itching.
Vascular disorders: flushing of the face.
Overdose of
Troxerutin has very low toxicity.
Overdose symptoms: agitation, nausea, headache and flushing.
In case of overdose, patients need to rinse their stomach, take activated charcoal (within an hour after administration), consult a doctor, if necessary, carry out symptomatic and supportive treatment.
Storage conditions
At a temperature not exceeding 25 ° C.
Keep out of the reach of children.
Expiration
3 years.
Do not use after the expiration date.
dosage form
capsules
