Description
Briefly about the product
Otrivin nasal spray dosed for children 0.05%.
Moisturizing formula reduces symptoms of irritation and dryness of the nasal mucosa.
May be used in children older than 2 years. Relieves congestion after 2 minutes, maintaining the effect up to 12 hours *.
* Instructions for medical use, RU No. Ñ N011649 / 03 of 12.28.09
Description
Dosage nasal spray (for children) 0.05% in the form of a clear, colorless solution, practically odorless.
Release form
10 ml – bottles of high density polyethylene (1) with a pump-operated dosing device, tip and protective cap made of polyethylene – cardboard packs.
Pharmacological action
A vasoconstrictor drug for local use in ENT practice (decongestant). Xylometazoline has an alpha-adrenomimetic effect. Causes narrowing of the blood vessels of the nasal mucosa, eliminating edema and hyperemia of the mucous membrane of the nasopharynx. Facilitates nasal breathing in rhinitis.
Otrivin ® is well tolerated by patients with sensitive mucous membranes, its effect does not interfere with the separation of mucus. The drug has a balanced pH value characteristic of the nasal cavity.
The composition of the drug includes inactive components – sorbitol and hypromellose, which are moisturizers, which can reduce the symptoms of irritation and dryness of the nasal mucosa that occur with prolonged use of xylometazoline.
In therapeutic concentrations, the drug does not irritate the mucous membrane, does not cause hyperemia.
Action occurs 2 minutes after administration and lasts for 12 hours.
In vitro studies have shown that xylometazoline in humans suppresses the infectious activity of rhinovirus that causes the common cold.
Contraindications
– arterial hypertension
– tachycardia
– severe atherosclerosis
– glaucoma
– atrophic rhinitis
– hyperthyroidism
– surgical interventions in the brain
Used with caution in patients with diabetes mellitus, cardiovascular diseases, with increased sensitivity to adrenergic drugs, accompanied by symptoms of insomnia, dizziness, cardiac arrhythmia, tremor, high blood pressure.
Use during pregnancy and lactation
The drug should not be used during pregnancy.
During lactation, use is possible only under the supervision of a doctor and after a careful assessment of the risk-benefit ratio for the mother and the fetus.
Do not exceed recommended dose.
Composition
1 ml: – xylometazoline hydrochloride 500 mcg
Excipients:
sodium dihydrogen phosphate dihydrate – 5 mg,
sodium hydrogen phosphate dodecahydrate – 1.7 mg,
disodium edetate – 500 μg,
benzalkonium chloride (in the form of a 50% solution) – 100 μg,
sorbitol 70% – 20 thousand 4 mg,
sorbitol 4 mg,
. – 5 mg,
sodium chloride – 4 mg,
purified water – up to 1 ml.
Dosage and administration
For children from 2 to 5 years: 1 injection in each nasal passage 1-3 times / day.
For children from 6 to 11 years: 1-2 injections in each nasal passage 2-3 times / day.
Do not use more than 3 times / day. It is recommended to be applied the last time immediately before bedtime.
The drug should be used under adult supervision.
Side effects
Determination of the frequency of adverse reactions: very often 10) often ( 1/100, <1/10) infrequently ( 1/1000, <1/100) rarely ( 1/10 000, <1 / 1000) is very rare (<1/10 000). On the part of the immune system: very rarely – hypersensitivity reactions (angioedema, rash, itching). From the nervous system: often – headache rarely – insomnia, depression (with prolonged use in high doses). On the part of the sensory organs: very rarely – a violation of the clarity of visual perception. From the cardiovascular system: rarely – palpitations, increased blood pressure very rarely – tachycardia, arrhythmia. From the respiratory system: often – irritation and / or dryness of the mucous membrane of the nasopharynx, burning, tingling, sneezing, hypersecretion of the mucous membrane of the nasopharynx. From the digestive system: often – nausea rarely – vomiting. Local reactions: often a burning sensation at the site of use. If any of the above side effects are exacerbated, or if the patient has noticed any other side effects, he should inform the doctor. Drug Interaction Incompatible with MAO inhibitors and tricyclic antidepressants. Overdose Symptoms: xylometazoline, when used topically or accidentally, can cause severe dizziness, excessive sweating, sharp decrease in body temperature, headache, bradycardia, wheezing, wheezing. Following an increase in blood pressure, a sharp decrease can be observed. Treatment: Appropriate supportive measures should be taken with any suspected overdose, and in some cases immediate symptomatic treatment is indicated under the supervision of a physician. These measures should include monitoring the patient for several hours. In the case of severe poisoning with cardiac arrest, resuscitation should last at least 1 hour. Storage conditions The drug should be stored out of the reach of children at a temperature not exceeding 30 ° C. The Expiration of is 3 years. Deystvuyuschee substances xylometazoline Sirdlkp pharmacy terms and conditions without a prescription 60 pharmacist without prescription 60 p17ro60 p1789 Over-the-counter L Dosage form Dosage form nasal spray GSK Consumer Helsker SA, Switzerland
