Description
Release form
Injection.
Packing
10 ampoules of 10 ml.
Pharmacological action
Riboxin – a drug that improves tissue metabolism and energy supply, reduces tissue hypoxia. Derived from purine. Inosine can be considered as a precursor of ATP. It has an anabolic effect. Activates myocardial metabolism. Inosine increases the activity of a number of enzymes in the Krebs cycle, stimulates the synthesis of nucleotides. It inhibits the process of destruction of sarcolemma of ischemic cardiomyocytes and provides intracellular energy transport. By improving microcirculation, the drug reduces the size of the necrosis zone and myocardial ischemia.
Indications
Riboxin is prescribed for adults in the treatment of coronary heart disease, myocardial dystrophy, after myocardial infarction, heart rhythm disturbances caused by the use of cardiac glycosides.
Assign for hepatitis, cirrhosis, fatty liver caused by alcohol or drugs, and urocoproporphyria.
As a means of pharmacological protection of the kidneys from ischemia with a temporary disconnection of the kidney from blood circulation.
The drug improves the visual function of the open-angle form of glaucoma with intraocular pressure normalized under the influence of antihypertensive therapy.
Contraindications
Hypersensitivity to the drug.
Special instructions
Riboxin is not used for emergency correction of cardiac abnormalities.
Composition
1 ml of the solution contains 20 ml of inosine.
Dosage and administration
Riboxin solution 2% is administered intravenously. Enter slowly jet or drip (40-60 drops in 1 minute).
Treatment begins with the introduction of 10 ml (200 mg) 1 time per day. With good tolerance, the dose can be increased to 20 ml (400 mg) 1-2 times a day. The duration of treatment is 10-15 days.
For dropwise administration, a solution of riboxin in isotonic sodium chloride solution or 5% glucose solution is diluted to 250 ml.
Side effects
Allergic reactions in the form of urticaria, skin itching, skin hyperemia are possible (the drug is canceled).
Rarely: increased concentration of uric acid in the blood.
In case of prolonged use: aggravation of gout is possible.
Drug interaction
When used as part of complex therapy, riboxin helps increase the effectiveness of antiarrhythmic, antianginal and inotropic drugs.
Clinically significant interaction of Riboxin with drugs of other groups is not described.
Overdose
No overdose reported at this time.
Storage Conditions
In a dry, dark place at room temperature. Keep out of the reach and sight of children.
The Expiration of
is 3 years.
Active ingredient
Inosine
Terms leave through pharmacies
In retseptu
lekarstvennaja form
Solution for infusion
Upgrading PFC, Russia
