Description
Pharmacological action
Gentamicin sulfate is a broad-spectrum aminoglycoside antibiotic, active against most gram-negative and some gram-positive microorganisms, including Pseudomonas aeruginosa. Gentamicin sulfate inhibits the formation of peptide bonds during the biosynthesis of proteins on the ribosomes of bacterial cells. Dexamethasone is a glucocorticosteroid that has a pronounced anti-inflammatory, desensitizing, anti-allergic effect due to inhibition of the release of inflammatory mediators. Dexamethasone reduces the number of mast cells that produce hyaluronic acid, reduces the porosity of blood capillaries, stimulates the biosynthesis of lipocartins (special proteins) with decongestant activity. When instilled into the conjunctival sac, the drug easily penetrates into the tissues of the eye, providing a stable therapeutic level of active components. According to the degree of exposure to the organism of warm-blooded animals, Dekt-2 eye drops are low-hazard substances and, in recommended doses, do not have an irritating and sensitizing effect.
Indications
Assign to dogs and cats for therapeutic and prophylactic purposes in acute and chronic ophthalmic diseases of bacterial and allergic etiology, including conjunctivitis, blepharitis, keratitis, kerato-conjunctivitis, iritis and iridocyclitis. For the prevention of infectious complications after injuries, ingress of foreign bodies, in the period before and after eye surgery.
Contraindications
Individual intolerance in animals to the components of the drug, as well as ulcers and erosion of the cornea, glaucoma.
Composition of
in 1 ml of solution: 5 mg of gentamicin sulfate and 1 mg of dexamethasone, as well as auxiliary components.
Dosage and administration
Before using Decta-2, especially in the presence of profuse bleeding from the eyes, dried exudate crusts, they carry out preliminary hygienic treatment with a sterile gauze soaked in the preparation in the direction from the outer corner of the eye to the inside, gently clean the eyelids. Next, the drug is instilled into the conjunctival sac 2-3 drops 2-3 times a day for 5-10 days until the clinical signs of the disease disappear. If necessary, repeat the treatment. For the prevention of infectious complications after injuries, ingress of foreign bodies, before and after surgery on the eyes, Dektu-2 is used 1-2 drops three times a day for three days. Eye drops can be used with other medicines for animals.
Side effects of
In hypersensitive animals, allergic reactions are rare in rare cases. In these cases, the use of the drug is stopped.
