Description
Pharmacological action
Fluralaner, which is part of the drug, is an acaricide and insecticide. It is effective against ticks (Ixodes spp., Dermacentor spp., Haemaphysalis elliptica and Rhipicephalus sanguineus), as well as Sarcoptes spp., Otodectes spp. and fleas (Ctenocephalides spp.).
Fluralaner is a potent inhibitor of certain parts of the arthropod nervous system, acting antagonistically on potential-independent carrier channels for chlorine ions (GABA receptor and glutamate receptor).
After topical administration, fluralaner is rapidly absorbed into the coat, skin and adjacent tissues, from where it slowly enters the vascular system. The plateau level is reached in plasma 7-63 days after application, after which the concentration slowly decreases. Fluralaner is well distributed in tissues and reaches high concentrations in adipose tissue, liver, muscles and kidneys. Long-term preservation and slow elimination from plasma and the absence of intensive metabolism provide effective concentrations of fluralaner during the time interval between applications of the drug. Fluralaner is excreted unchanged with excrement and, to a very insignificant degree, with urine.
Indications
Bravecto Spot It is used by cats to treat and prevent tick and flea infections, as well as to treat otodectosis caused by Otodectes spp., in cats.
Can be used as part of a comprehensive treatment for allergic dermatitis caused by fleas.
The prophylactic effect of flea and tick infections in cats and dogs lasts for 12 weeks.
The effect after application of the drug develops within 12 hours (from fleas) and 48 hours (from ticks) for cats.
Recommended Use Immediately before use, open the bag and remove the pipette. When opening, the pipette must be held by the base or the upper rigid part under the cap in an upright position (cap up).
Twist’N’Use ™ cap rotate clockwise or counterclockwise one full revolution.
After the internal sealed membrane has collapsed, the pipette is open and ready for use. The cap is not removable.
For simplicity and ease of application, the cat should stand or lie so that the back is in a horizontal position.
Gently squeeze the dropper and apply all its contents directly to the cat’s skin. When processing cats weighing more than 6.25 kg, the drug should be applied twice pointwise on the body of the animal.
