Description
Pharmacological action
Pharmacotherapeutic group:
Antimicrobial agent – sulfonamide.
ATX:
D.06.BA Sulfanilamides
Pharmacodynamics:
Streptocide is an antimicrobial bacteriostatic agent, sulfonamide. The mechanism of action is due to competitive antagonism with para-aminobenzoic acid (PANK), inhibition of dihydropteroate synthase, impaired synthesis of tetrahydrofolate acid, necessary for the synthesis of purines and pyrimidipes. Active against gram-positive and gram-negative cocci, Escherichia coli. Shigella spp., Vibrio cholerae, Clostridium perfringens, Bacillus anthracis, Corynebacterium diphtheriae, Yersinia pestis. Chlamydia spp., Actinomyces israelii. Toxoplasma gondii. When applied to the skin, it contributes to the rapid healing of wounds and epithelization of erosion.
Indications
As part of complex therapy: purulent wounds, infected burns (I-II degree) and other purulent-inflammatory processes of soft tissues.
Contraindications
– Hypersensitivity to sulfanilamides
– hepatic or renal insufficiency
– suppression of bone marrow hematopoiesis
– anemia
– chronic heart disease – chronic heart disease thyrotoxicosis
– pregnancy and the period of breastfeeding.
Caution:
Childhood.
Use during pregnancy and lactation
The drug is contraindicated in pregnancy and during breastfeeding.
Special instructions
A generous alkaline drink is recommended during therapy. If necessary, prescribe antimicrobials inside.
Impact on the ability to drive transp. Wed and fur .:
Given the side effects of the drug, caution should be exercised when driving vehicles, mechanisms.
Composition
Active ingredient: Sulfanilamide 2.0 g.
Dosage and administration
Topically, apply directly to the affected surface (in the form of a powder for external use). Dressings are performed in 1-2 days. Maximum doses for adults: single dose – 5 g, daily dose – 15 g. For children over 3 years old – 300 mg – single dose, daily dose 300 mg.
Side effects
With hypersensitivity to sulfa drugs, allergic reactions are possible, the development of which requires immediate discontinuation of the drug. In addition, headache, dizziness, nausea, vomiting, dyspepsia, cyanosis, leukopenia, agranulocytosis, crystalluria. If any of the side effects indicated in the instructions are aggravated, or if you notice any other side effects not listed in the instructions, inform your doctor.
Drug Interactions
Myelotoxic drugs enhance the hematotoxicity of the drug.
Overdose
Symptoms: nausea, vomiting, intestinal colic, dizziness, headache, drowsiness, depression, fainting, confusion, blurred vision, fever, hematuria, crystalluria with prolonged overdose – thrombocytopenia, leukopenia, leukopenia, leukopenia.
Treatment: heavy drinking with accidental ingestion – gastric lavage.
Storage conditions
Dry, a place protected from light at a temperature of no higher than 25 ° C. Keep out of the reach of children.
Expiration
5 years.
Deystvuyuschee substances
Sulfanylamide
Appointment
Prescription physician, Adult
Indications
From pyoderma, Burns, From skin infections, From boils, Purulent wounds, From bedsores
