Description
Pharmacological action
Xylometazoline belongs to the group of local vasoconstrictors (decongestants) with alpha-adrenomimetic activity.
The drug facilitates nasal 2 respiration by reducing swelling and hyperemia of the mucous membrane, and also improves discharge discharge.
The action of the drug occurs a few minutes after its use and lasts up to 10 hours.
Indications
Acute respiratory infections with rhinitis (runny nose), acute allergic rhinitis, sinusitis, otitis media (as part of combination therapy to reduce swelling of the nasopharynx), hay fever, eustachiitis, to facilitate rhinoscopy.
Contraindications
Hypersensitivity to xylometazoline and other components of the drug, hypertension, tachycardia, severe atherosclerosis, glaucoma, atrophic rhinitis, surgical interventions on the meninges (history), children under 2 years old for 0.05% solution (0.0005 g / ml), children under 6 years old for 0.1% solution (0.001 g / ml ), thyrotoxicosis, conditions after transsphenoidal hypophysectomy, pregnancy.
Do not use during therapy with monoamine oxidase inhibitors and tricyclic antidepressants (including the period of 14 days after their withdrawal), as well as with other drugs that increase blood pressure.
With caution
Breastfeeding period, coronary heart disease (angina pectoris), diabetes mellitus, prostatic hyperplasia, hyperthyroidism, porphyria, pheochromocytoma, patients with hypersensitivity to adrenergic drugs, accompanied by insomnia, dizziness, arrhythmia, trematosis.
Recommended Uses for
Intranasal.
Before use it is necessary to clear the nasal passages. Adults and children over 6 years of age by 1 injection of a 0.1% xylometazoline solution in each nasal passage 2-3 times a day. Do not use for more than 5-7 days, because xylometazoline can cause swelling of the nasal mucosa, leading to its atrophy.
Children aged 2 to 6 years apply a 0.05% xylometazoline solution, 1 injection into each nasal passage 1-2 times a day. Do not use the drug more than 3 times a day.
The duration of the drug in children is determined by the doctor.
Special instructions
Prolonged use (more than 7 days) can lead to reactive hyperemia of the nasal mucosa and atrophy of the nasal mucosa.
Do not exceed recommended doses. Benzalkonium chloride, which is part of the drug, can cause irritation and swelling of the nasal mucosa.
It is not recommended to use the drug continuously for more than 7 days.
Avoid contact with the drug
Composition
Active ingredient: Xylometazoline hydrochloride 1.0 mg
Excipients:
Benzalkonium chloride in terms of anhydrous 0.15 mg
Disodium edetate dihydrate 0.5 mg
Potassium dihydrogen phosphate 3.63 mg sodium sulfide
Sodium Chloride 9.0 mg
Purified water to 1.0 ml
Side effects
With frequent and / or prolonged use – irritation and / or dryness of the nasopharyngeal mucosa, burning, paresthesia, sneezing, hypersecretion rarely – swelling of the nasal mucosa, nosebleed, palpitations, tachycardia, arrhythmia, pressure, nausea, vomiting, headache, insomnia, visual impairment, depression (with prolonged use of high doses), anxiety, fatigue, hallucinations and convulsions (mainly in children), hypersensitivity reactions (an ionevrotichesky edema, skin rash, itching).
benzalkonium chloride, which is part of the drug, can cause irritation and swelling of the mucous membrane of the nasal cavity.
Overdose of
Symptoms:
with an overdose or accidental ingestion of the drug, the following symptoms may develop: nausea, vomiting, cyanosis, fever, a significant decrease in body temperature, shortness of breath, dizziness, increased sweating, headache, bradycardia, arrhythmia, tachycardia, increased blood pressure, followed by a decrease in blood pressure, respiratory depression, coma, and convulsions. In young children with an overdose, dominant central effects are often observed with convulsions, coma and bradycardia, apnea, as well as an increase in blood pressure, which follows hypotension.
Treatment: symptomatic under medical supervision. Patient monitoring should be within a few hours.
In case of accidental ingestion – gastric lavage, intake of activated carbon.
Storage conditions
At a temperature not exceeding 25 ° C. Keep out of the reach of children.
Expiration
3 years. Do not use after the expiration date indicated on the package
Deystvuyuschee substances
xylometazoline
Without prescription Ia otpuska IZ
pharmacies without a prescription
dosage form
nasal spray
