Description
Packing
6 pcs
Pharmacological action
Candide-B6 – antifungal.
Violates the synthesis of ergosterol, which is part of the cell membrane of fungi, which causes a change in its structure and properties and leads to cell lysis.
Pharmacodynamics
Clotrimazole is susceptible to dermatophytes, yeast fungi (genus Candida, Torulopsis glabrata, genus Rhodotorula), mold fungi, as well as the pathogen Pityriasis versicolor (colorful lichen) and the pathogen of erythrasma.
In addition, it has an antimicrobial effect against gram-positive (staphylococci and streptococci) and gram-negative bacteria (Bacteroides, Gardnerella vaginalis), as well as against Trichomonas vaginalis, Malassezia furfur, Corynebacterium minutissimum.
Pharmacokinetics
Resorption is 3 10% of the administered dose.
Indications
– genital infections caused by yeasts of the genus Candida and / or Trichomonas vaginalis (candida vulvovaginitis, trichomoniasis)
– genital superinfection caused by bacteria sensitive to clotrimazole, mixed infections.
Contraindications
Hypersensitivity reactions to clotrimazole.
Special instructions
To prevent urogenital reinfection, simultaneous treatment of both sexual partners is necessary.
With trichomoniasis, other drugs with a systemic effect, such as metronidazole, should be prescribed in conjunction with Candide-B6 for more successful treatment.
Vaginal tablets are not recommended for use during menstruation.
Composition
1 tablet contains:
Active substance:
– clotrimazole 100 mg
Excipients:
acid adipic
corn starch
colloidal silica
lactose
magnesium stearate
methyl parahydroxybenzoate (Nipagin)
sodium hydrogencarbonate
sodium glycolate (Primogel)
Povidone K-30
propyl parahydroxybenzoate (nipazole)
talc.
Dosage and Administration
Topically. Intravaginally, deeply administered in the supine position with slightly bent legs.
1 tablet (100 mg) 1 time per day (in the evening) for 6 days.
A second course of treatment is possible after consulting a doctor.
Side effects
Rarely – a sensation of a slight burning sensation immediately after administration of the pill, which disappears with continued treatment.
Drug Interactions
Vaginal administration reduces the activity of amphotericin B and other polyene antibiotics.
When used concomitantly with nystatin, Candida-B6 activity may decrease.
Storage Conditions
In a dry, dark place at a temperature not exceeding 25 ° C.
Expiration
4 years.
Active ingredient
clotrimazole
Conditions of release from drugstores
Without prescription
lekarstvennaja form
tablets vahynaln e
Prescription
Nursing mothers, Adults, Pregnant II and III trimester intended physician
Indications Indications
from inflammation of the female genital organs, From thrush
Glenmark Pharmaceuticals Ltd, India
